Evidence map›Paper›PMID 33391265›Full record

ArticleFrontiers in immunology2020

Alterations of the Fecal Microbiota in Chinese Patients With Multiple Sclerosis.

Zongxin Ling, Yiwen Cheng, Xiumei Yan, Li Shao, Xia Liu, Dajin Zhou, Lijuan Zhang, Kunqiang Yu, Longyou Zhao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 4 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Changes in Gut Microbiota and Multiple Sclerosis: A Systematic Review.International journal of environmental research and public health · 2023
    Pooled it
  4. Probiotics for the treatment of depression and its comorbidities: A systemic review.Frontiers in cellular and infection microbiology · 2023
    Pooled it
  5. Article
  6. Article
  7. Review
  8. Impact of carbapenem-resistantMicrobiology spectrum · 2026
    Article
  9. Article
  10. Impact of a GABA-ProducingFASEB bioAdvances · 2026
    Article
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  14. Review
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  16. Article
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  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Zongxin LingCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yiwen ChengCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Xiumei YanDepartment of Laboratory Medicine, Lishui Second People's Hospital, Lishui, China.
Li ShaoHangzhou Normal University, Hangzhou, China.
Xia LiuDepartment of Intensive Care Unit, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Dajin ZhouDepartment of Laboratory Medicine, Lishui Second People's Hospital, Lishui, China.
Lijuan ZhangDepartment of Laboratory Medicine, Lishui Second People's Hospital, Lishui, China.
Kunqiang YuDepartment of Laboratory Medicine, Lishui Second People's Hospital, Lishui, China.
Longyou ZhaoDepartment of Laboratory Medicine, Lishui Second People's Hospital, Lishui, China.
Xian Yang Central Hospital · CNZhejiang University · CNLishui City People's Hospital · CNHangzhou Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mounting evidence indicates that alterations in the intestinal microbiota may be associated with neurological disorders such as multiple sclerosis (MS). MS is a putative autoimmune disease of the central nervous system. However, it has not been determined whether the intestinal microbiota and host immune status are altered in Chinese patients with stable MS. In our study, 22 Chinese patients with stable MS and 33 healthy controls were enrolled for fecal microbiota analysis and host immunity evaluation. The microbial diversity and composition, bacterial co-occurrence correlations, predictive functional profiles, and microbiota-cytokine correlations between the two groups were compared. We observed that while the overall structure of the fecal microbiota did not change significantly, the abundances of several key functional bacteria, primarily

Indexed as

Gastrointestinal MicrobiomeAdultAsian PeopleCytokinesFecesFemaleHumansMaleMultiple SclerosisCytokinesbutyrateFaecalibacteriumfecal microbiotaIL-17multiple sclerosis

Identifiers

PMID33391265
PMCPMC7772405
OpenAlexW3110917631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.