Evidence map›Paper›PMID 33391223›Full record

ReviewFrontiers in microbiology2020

Targeting the Malaria Parasite cGMP-Dependent Protein Kinase to Develop New Drugs.

David A Baker, Alexios N Matralis, Simon A Osborne, Jonathan M Large, Maria Penzo

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Frontiers in parasitology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. New targets for antimalarial drug discovery.Current opinion in microbiology · 2022
    Review
  12. Article
  13. Open biology · 2022
    Article
  14. Adapt or Die: Targeting Unique Transmission-Stage Biology for Malaria Elimination.Frontiers in cellular and infection microbiology · 2022
    Review
  15. Article
  16. Review
  17. Malaria parasite egress at a glance.Journal of cell science · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

David A BakerFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Alexios N Matralis"Alexander Fleming" Biomedical Sciences Research Center, Vari, Greece.
Simon A OsborneLifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
Jonathan M LargeLifeArc, Accelerator Building, Open Innovation Campus, Stevenage, United Kingdom.
Maria PenzoFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
LifeArc · GBLondon School of Hygiene & Tropical Medicine · GBAlexander Fleming Biomedical Sciences Research Center · GR

Funding

Wellcome Trust
6 · The paper itself

Abstract

The single-celled apicomplexan parasite

Indexed as

cyclic GMPdrug discoverymalariaPlasmodium falciparumsignal transduction

Identifiers

PMID33391223
PMCPMC7773720
OpenAlexW3112726550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.