Evidence map›Paper›PMID 33391186›Full record

ArticleFrontiers in endocrinology2020

Fluconazole for Hypercortisolism in Cushing's Disease: A Case Report and Literature Review.

Yiming Zhao, Weiwei Liang, Feng Cai, Qun Wu, Yongjian Wang

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Clinical efficacy and safety of fluconazole treatment in patients with Cushing's syndrome.Therapeutic advances in endocrinology and metabolism · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yiming ZhaoDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
Weiwei LiangDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
Feng CaiDepartment of Neurosurgery, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
Qun WuDepartment of Neurosurgery, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
Yongjian WangDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
Second Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cushing's disease is associated with an increased risk of pulmonary fungal infection, which could be a relative contraindication for pituitary adenoma excision surgery. Case: We report a case of a patient with Cushing's disease and pulmonary Conclusion: Cushing's disease can be effectively treated with fluconazole to normalize cortisol concentration prior to pituitary surgery. Fluconazole is an alternative treatment especially in Cushing's disease patients with cryptococcal pneumonia.

Indexed as

Antifungal AgentsBrainCryptococcosisCryptococcus neoformansCushing SyndromeFemaleFluconazoleHumansLungLung Diseases, FungalMagnetic Resonance ImagingMiddle AgedNeurosurgical ProceduresPituitary ACTH HypersecretionTomography, X-Ray ComputedTreatment OutcomeAntifungal AgentsFluconazoleCushing’s diseaseCushing’s syndromefluconazolehypercortisolismmedical treatment

Identifiers

PMID33391186
PMCPMC7774647
OpenAlexW3112745645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.