ArticleFrontiers in psychiatry2020
Altered Static and Dynamic Functional Connectivity of Habenula Associated With Suicidal Ideation in First-Episode, Drug-Naïve Patients With Major Depressive Disorder.
Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- The habenula in mood disorders: A systematic review of human studies.Molecular psychiatry · 2025Pooled it
- Light Therapy Alleviates Addiction-Related Symptoms and Reshapes Habenula and Midbrain Pathways.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Trial
- Ecologically-Valid Emotion Signatures Enhance Mood Disorder Diagnostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The Habenula's role in major depressive disorder: recent insights from preclinical and human studies.Translational psychiatry · 2026Review
- Review of Dynamic Resting-State Methods in Neuroimaging: Applications to Depression and Rumination.Human brain mapping · 2025Review
- Existence of Dynamic Functional Connectivity Variations of Brain Networks in Psychogenic Non-Epileptic Seizures Through Resting-state Functional Magnetic Resonance Imaging.Journal of biomedical physics & engineering · 2025Article
- Abnormal intrahemispheric and interhemispheric dynamic functional connectivity density in male alcohol use disorder.Frontiers in psychiatry · 2025Article
- Modulation of habenular and nucleus accumbens functional connectivity by ketamine in major depression.Brain and behavior · 2024Article
- Characterizing the temporal dynamics of intrinsic brain activities in depressed adolescents with prior suicide attempts.European child & adolescent psychiatry · 2024Article
- Disrupted functional connectivity of the habenula links psychomotor retardation and deficit of verbal fluency and working memory in late-life depression.CNS neuroscience & therapeutics · 2024Article
- Altered habenular connectivity in chronic low back pain: An fMRI and machine learning study.Human brain mapping · 2023Article
- Pre-treatment functional connectivity of the cingulate cortex predicts anti-suicidal effects of serial ketamine infusions.European psychiatry : the journal of the Association of European Psychiatrists · 2023Article
- Spontaneous transient states of fronto-temporal and default-mode networks altered by suicide attempt in major depressive disorder.European archives of psychiatry and clinical neuroscience · 2022Article
- Temporal Stability of Dynamic Default Mode Network Connectivity Negatively Correlates with Suicidality in Major Depressive Disorder.Brain sciences · 2022Article
- Postmortem gene expression profiles in the habenulae of suicides: implication of endothelial dysfunction in the neurovascular system.Molecular brain · 2022Article
- Commentary: Aberrant dynamic functional connectivity of posterior cingulate cortex subregions in major depressive disorder with suicidal ideation.Frontiers in neuroscience · 2022Article
- The Role of the Lateral Habenula in Suicide: A Call for Further Exploration.Frontiers in behavioral neuroscience · 2022Review
- Suicidal Ideation Is Associated With Reduced Functional Connectivity and White Matter Integrity in Drug-Naïve Patients With Major Depression.Frontiers in psychiatry · 2022Article
- More Than Just Statics: Temporal Dynamic Changes in Inter- and Intrahemispheric Functional Connectivity in First-Episode, Drug-Naive Patients With Major Depressive Disorder.Frontiers in human neuroscience · 2022Article
- Altered Variability and Concordance of Dynamic Resting-State Functional Magnetic Resonance Imaging Indices in Patients With Major Depressive Disorder and Childhood Trauma.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Investigating the neurobiological mechanism of suicidal ideation (SI) in major depressive disorder (MDD) may be beneficial to prevent the suicidal behavior. Mounting evidence showed that habenula contributed to the etiology of MDD. The habenula is a key brain region that links the forebrain to midbrain, crucial for the processing of reward and aversion. The aim of the present study was to identify whether first-episode, drug-naive MDD patients with SI displayed altered habenula neural circuitry. Forty-three and 38 drug-naïve patients with first-episode MDD with or without SI (SI+/- group) and 35 healthy control subjects (HC) underwent resting-state functional magnetic resonance imaging. The whole-brain habenula static (sFC) and dynamic functional connectivity (dFC) were calculated to identify regions showing significant difference among these three groups followed by region of interest to region of interest
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Registered trials
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