Evidence map›Paper›PMID 33390994›Full record

ReviewFrontiers in pharmacology2020

COVID-19 Disease and Vitamin D: A Mini-Review.

Mohamed Said Boulkrane, Victoria Ilina, Roman Melchakov, Julia Fedotova, Filippo Drago, Lucia Gozzo, Undurti Narasimha Das, A M Abd El-Aty, Denis Baranenko

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Effect of vitamin DClinics (Sao Paulo, Brazil) · 2024
    Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Relationship between Vitamin D and Immunity in Older People with COVID-19.International journal of environmental research and public health · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Co-administration of vitamin D3 andAnnals of microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Mohamed Said BoulkraneInternational Research Centre "Biotechnologies of the Third Millennium", ITMO University, Saint-Petersburg, Russia.
Victoria IlinaInternational Research Centre "Biotechnologies of the Third Millennium", ITMO University, Saint-Petersburg, Russia.
Roman MelchakovInternational Research Centre "Biotechnologies of the Third Millennium", ITMO University, Saint-Petersburg, Russia.
Julia FedotovaLaboratory of Neuroendocrinology, I.P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia.
Filippo DragoDepartment of Biomedical and Biotechnological Sciences, Biological Tower, School of Medicine, University of Catania, Catania, Italy.
Lucia GozzoDepartment of Biomedical and Biotechnological Sciences, Biological Tower, School of Medicine, University of Catania, Catania, Italy.
Undurti Narasimha DasUND Life Sciences, Battle Ground, WA, United States.
A M Abd El-AtyDepartment of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Denis BaranenkoInternational Research Centre "Biotechnologies of the Third Millennium", ITMO University, Saint-Petersburg, Russia.
ITMO University · RUUniversity of Catania · ITCairo University · EGPavlov Institute of Physiology of the Russian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel coronavirus disease (COVID-19) pandemic caused by SARS-CoV-2, for which there is no effective treatment except employing prevention strategies, has already instituted significant number of deaths. In this review, we provide a scientific view on the potential role of vitamin D in SARS-CoV-2 virus/COVID-19 disease. Vitamin D is well-known to play a significant role in maintaining the immune health of an individual. Moreover, it induces antimicrobial peptide expression that can decrease viral replication and regulate the levels of pro-inflammatory/anti-inflammatory cytokines. Therefore, supplementation of vitamin D has the potential to reduce the incidence, severity and the risk of death from pneumonia resulting from the cytokine storm of many viral infections including COVID-19. We suggest that supplementation of subjects at high risk of COVID-19 with vitamin D (1.000 to 3.000 IU) to maintain its optimum serum concentrations may be of significant benefit for both in the prevention and treatment of the COVID-19.

Indexed as

COVID 19respiratory tract infectionSARS-CoV-2vitamin D3vitamin D3 receptor

Identifiers

PMID33390994
PMCPMC7773655
OpenAlexW3111886139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.