Evidence map›Paper›PMID 33390949›Full record

ArticleFrontiers in pharmacology2020

Structural Characterization and Immune Activity Screening of Polysaccharides With Different Molecular Weights From Astragali Radix.

Ke Li, Y-X Cao, S-M Jiao, G-H Du, Y-G Du, X-M Qin

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  8. Effects of Low-Protein Amino Acid-Balanced Diets andAnimals : an open access journal from MDPI · 2025
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  12. Chemical Composition and Therapeutic Effects of Several Astragalus Species (Fabaceae).Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ke LiModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China.
Y-X CaoModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China.
S-M JiaoInstitute of Process Engineering, Chinese Academy of Sciences, Beijing, China.
G-H DuInstitute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Y-G DuInstitute of Process Engineering, Chinese Academy of Sciences, Beijing, China.
X-M QinModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saccharides are the most abundant substance with the strongest immunological activity in Astragali Radix (AR). However, systematic structure study and immunoactivity screening of polysaccharides with different molecular weights (Mw) in AR have yet to be conducted. In this study, Astragalus polysaccharides (APSs) were divided into three fragments of different Mw values, >2,000 kDa (APS-Ⅰ), about 10 kDa (APS-Ⅱ), and about 300 Da (APS-Ⅲ), by using ultrafiltration for the first time. The structural differences of the three products were determined on the basis of monosaccharide composition, FT-IR spectrum, linkage analysis, and nuclear magnetic resonance analysis. Cellular immune activity experiments

Indexed as

Astragalus polysaccharidedifferent molecular weightimmunomodulatory activitynonspecific and specificstructure characterization

Identifiers

PMID33390949
PMCPMC7774520

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