Evidence map›Paper›PMID 33390942›Full record

ArticleFrontiers in pharmacology2020

The Natural Compound Oblongifolin C Exhibits Anticancer Activity by Inhibiting HSPA8 and Cathepsin B

Li Han, Danqing Xu, Zhichao Xi, Man Wu, Wan Najbah Nik Nabil, Juan Zhang, Hua Sui, Wenwei Fu, Hua Zhou, Yuanzhi Lao and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Li HanSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Danqing XuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhichao XiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Man WuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wan Najbah Nik NabilSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Juan ZhangSchool of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Hua SuiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wenwei FuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hua ZhouInstitute of Cardiovascular Disease of Integrated Traditional Chinese and Western Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yuanzhi LaoSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Gang XuState Key Laboratory of Phytochemistry and Plant Resources in West China and Yunnan Key Laboratory of National Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
Cheng GuoSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hongxi XuInstitute of Cardiovascular Disease of Integrated Traditional Chinese and Western Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Shanghai University of Traditional Chinese Medicine · CNChinese University of Hong Kong · CNKunming Institute of Botany · CNShuguang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PPAPs (Polycyclic polyprenylated acylphloroglucinols) are a class of compounds with diverse bioactivities, including anticancer effects. Oblongifolin C (OC) is a PPAP isolated from the plant of

Indexed as

cathepsin BHSPA8natural compoundsoblongifolin Cprotein fishing

Identifiers

PMID33390942
PMCPMC7773843
OpenAlexW3111410499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.