Evidence map›Paper›PMID 33390776›Full record

ArticleInternational journal of medical sciences2021

Oridonin inhibits epithelial-mesenchymal transition of human nasopharyngeal carcinoma cells by negatively regulating AKT/STAT3 signaling pathway.

Wei Liu, Gaobo Huang, Yang Yang, Ruixia Gao, Shaoqiang Zhang, Bo Kou

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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  12. Terpenoids' anti-cancer effects: focus on autophagy.Apoptosis : an international journal on programmed cell death · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wei LiuDepartment of Vascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, People's Republic of China.
Gaobo HuangNational Local Joint Engineering Research Center for Precision Surgery and Regenerative Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, People's Republic of China.
Yang YangDepartment of Cadiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, People's Republic of China.
Ruixia GaoSchool of Science, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, People's Republic of China.
Shaoqiang ZhangDepartment of Otorhinolaryngology-Head&Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, People's Republic of China.
Bo KouDepartment of Otorhinolaryngology-Head&Neck Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province 710061, People's Republic of China.
First Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oridonin, derived from

Indexed as

AcetatesAntigens, CDAntineoplastic Agents, PhytogenicBenzopyransCadherinsCell Line, TumorDiterpenes, KauraneDose-Response Relationship, DrugEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansIsodonNasopharyngeal CarcinomaNasopharyngeal NeoplasmsNuclear ProteinsPhosphorylationAcetatesAKT1 protein, humanAKT activator SC79Antigens, CDAntineoplastic Agents, PhytogenicBenzopyransCadherinsCDH1 protein, humanDiterpenes, KauraneNuclear ProteinsoridoninProto-Oncogene Proteins c-aktSTAT3 protein, humanSTAT3 Transcription FactorTWIST1 protein, humanTwist-Related Protein 1VimentinVIM protein, humanAKTepithelial-mesenchymal transitionnasopharyngeal carcinomaoridoninSTAT3

Identifiers

PMID33390776
PMCPMC7738957
OpenAlexW3097718289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.