Evidence map›Paper›PMID 33390597›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2021

Evaluation of bovine respiratory syncytial virus (BRSV) and bovine herpesvirus (BHV) specific antibody responses between heterologous and homologous prime-boost vaccinated western Canadian beef calves.

Nathan E N Erickson, Adam Berenik, Herbert Lardner, Stacey Lacoste, John Campbell, Sheryl Gow, Cheryl Waldner, John Ellis

Abstract read
PubMed Full text at PMC
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Comparing clinical and immunologic response efficacy of systemic primeThe Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Article
  3. Article
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  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nathan E N EricksonDepartment of Large Animal Clinical Sciences (Erickson, Berenik, Campbell, Gow, Waldner), Department of Microbiology (Lacoste, Ellis), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Lardner).
Adam BerenikDepartment of Large Animal Clinical Sciences (Erickson, Berenik, Campbell, Gow, Waldner), Department of Microbiology (Lacoste, Ellis), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Lardner).
Herbert LardnerDepartment of Large Animal Clinical Sciences (Erickson, Berenik, Campbell, Gow, Waldner), Department of Microbiology (Lacoste, Ellis), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Lardner).
Stacey LacosteDepartment of Large Animal Clinical Sciences (Erickson, Berenik, Campbell, Gow, Waldner), Department of Microbiology (Lacoste, Ellis), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Lardner).
John CampbellDepartment of Large Animal Clinical Sciences (Erickson, Berenik, Campbell, Gow, Waldner), Department of Microbiology (Lacoste, Ellis), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Lardner).
Sheryl GowDepartment of Large Animal Clinical Sciences (Erickson, Berenik, Campbell, Gow, Waldner), Department of Microbiology (Lacoste, Ellis), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Lardner).
Cheryl WaldnerDepartment of Large Animal Clinical Sciences (Erickson, Berenik, Campbell, Gow, Waldner), Department of Microbiology (Lacoste, Ellis), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Lardner).
John EllisDepartment of Large Animal Clinical Sciences (Erickson, Berenik, Campbell, Gow, Waldner), Department of Microbiology (Lacoste, Ellis), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Lardner).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine respiratory disease (BRD) is an economically important cause of morbidity and mortality in beef calves. Control of BRD is most often addressed through "homologous" vaccination utilizing the same injectable modified-live viral (MLV) vaccine for both priming and boosting. Heterologous prime-boosting uses different routes and antigenic forms for priming and boosting. Three vaccine protocols were compared: an injectable (IJ) MLV (IJ-MLV) group (IJ-MLV priming at ~48 days and boosted with IJ-MLV at weaning), intranasal (IN) MLV (IN-MLV) group (intranasal priming with MLV at ~24 hours, boosted twice with an IJ-MLV), and intranasal killed viral (IN-KV) group (primed with an IN-MLV at ~24 hours, boosted twice with an IJ-KV). Serum antibody concentrations determined by enzyme-linked immunosorbent assays (ELISAs) were compared and the IN-KV group had significantly higher BRSV-specific antibody concentrations after boosting compared with the 2 homologous groups. No differences in BHV-specific antibody concentrations were observed between any of the groups.

Indexed as

Cattle DiseasesHerpesvirus 1, BovineRespiratory Syncytial Virus, BovineViral VaccinesAnimalsAntibodies, ViralAntibody FormationCanadaCattleAntibodies, ViralViral Vaccines

Identifiers

PMID33390597
PMCPMC7739395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.