Evidence map›Paper›PMID 33390039›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Direct Actions of AT

Matthew A Sparks, Fitra Rianto, Edward Diaz, Ritika Revoori, Thien Hoang, Lucas Bouknight, Johannes Stegbauer, Anuradha Vivekanandan-Giri, Phillip Ruiz, Subramaniam Pennathur and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Immune and Metabolic Mechanisms of Endothelial Dysfunction.International journal of molecular sciences · 2024
    Review
  2. The immunology of heart failure with preserved ejection fraction.Clinical science (London, England : 1979) · 2023
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Vascular control of kidney epithelial transporters.American journal of physiology. Renal physiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Matthew A SparksFrom the Division of Nephrology, Department of Medicine (M.A.S., F.R., E.D., R.R., T.H., L.B., J.S., S.D.C., T.M.C.), Duke University School of Medicine, Durham, NC.
Fitra RiantoFrom the Division of Nephrology, Department of Medicine (M.A.S., F.R., E.D., R.R., T.H., L.B., J.S., S.D.C., T.M.C.), Duke University School of Medicine, Durham, NC.
Edward DiazFrom the Division of Nephrology, Department of Medicine (M.A.S., F.R., E.D., R.R., T.H., L.B., J.S., S.D.C., T.M.C.), Duke University School of Medicine, Durham, NC.
Ritika RevooriFrom the Division of Nephrology, Department of Medicine (M.A.S., F.R., E.D., R.R., T.H., L.B., J.S., S.D.C., T.M.C.), Duke University School of Medicine, Durham, NC.
Thien HoangFrom the Division of Nephrology, Department of Medicine (M.A.S., F.R., E.D., R.R., T.H., L.B., J.S., S.D.C., T.M.C.), Duke University School of Medicine, Durham, NC.
Lucas BouknightFrom the Division of Nephrology, Department of Medicine (M.A.S., F.R., E.D., R.R., T.H., L.B., J.S., S.D.C., T.M.C.), Duke University School of Medicine, Durham, NC.
Johannes StegbauerFrom the Division of Nephrology, Department of Medicine (M.A.S., F.R., E.D., R.R., T.H., L.B., J.S., S.D.C., T.M.C.), Duke University School of Medicine, Durham, NC.
Anuradha Vivekanandan-GiriDivision of Nephrology, Department of Medicine, Michigan University Medical Center, Ann Arbor (A.V.-G., S.P.).
Phillip RuizDepartment of Surgery and Pathology, University of Miami, FL (P.R.).
Subramaniam PennathurDivision of Nephrology, Department of Medicine, Michigan University Medical Center, Ann Arbor (A.V.-G., S.P.).
Dennis M AbrahamDivision of Cardiology, Department of Medicine (D.M.A.), Duke University School of Medicine, Durham, NC.
Susan B GurleyDivision of Nephrology and Hypertension, Department of Medicine, Oregon Health and Sciences University, Portland (S.B.G.).
Steven D CrowleyFrom the Division of Nephrology, Department of Medicine (M.A.S., F.R., E.D., R.R., T.H., L.B., J.S., S.D.C., T.M.C.), Duke University School of Medicine, Durham, NC.
Thomas M CoffmanFrom the Division of Nephrology, Department of Medicine (M.A.S., F.R., E.D., R.R., T.H., L.B., J.S., S.D.C., T.M.C.), Duke University School of Medicine, Durham, NC.
Duke University · USUniversity Medical Center · USOregon Health & Science University · USUniversity of Miami · US

Funding

University of Michigan O'Brien Kidney Translational Core CenterP30DK081943 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PENNATHUR, SUBRAMANIAM · 2008 to 2022
$12.9M
Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI GURLEY, SUSAN BAILEY · 2012 to 2016
$5.9M
ANGIOTENSIN RECEPTOR GENES AND BLOOD PRESSURE REGULATIONR01HL056122 · NHLBI · DUKE UNIVERSITY · PI COFFMAN, THOMAS M · 1997 to 2010
$3.2M
AT1 Angiotensin Receptors in the Renal Circulation Control Blood PressureIK2BX002240 · VA · DURHAM VA MEDICAL CENTER · PI SPARKS, MATTHEW AARON · 2014 to 2018
–
BLRD VA IK2 BX002240NHLBI NIH HHS R01 HL056122NIDDK NIH HHS P30 DK081943NIDDK NIH HHS P30 DK096493
6 · The paper itself

Abstract

Activation of AT

Indexed as

Angiotensin IIAnimalsCardiomegalyHypertensionMiceMice, KnockoutMice, TransgenicMyocardiumMyocytes, CardiacReceptor, Angiotensin, Type 1Renin-Angiotensin SystemVascular ResistanceAngiotensin IIReceptor, Angiotensin, Type 1hypertensionhypertrophymyocyte, cardiacrenin-angiotensin systemtransgenes

Identifiers

PMID33390039
PMCPMC7803456
OpenAlexW3119532310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.