Evidence map›Paper›PMID 33389978›Full record

ArticleTurkish journal of pharmaceutical sciences2020

Issam Mohammed Abushammala, Elham Abed Abuwaked, Hanan Mohammed Fayyad, Ahmed Fadel Elqedra, Mai Abed Alrahman Ramadan, Ihab Mustafa Almasri

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Issam Mohammed AbushammalaAl-Azhar University-Gaza Faculty of Pharmacy, Department of Pharmaceutics and Industrial Pharmacy, Gaza, Palestine.ORCID 0000-0002-3371-4718
Elham Abed AbuwakedAl-Azhar University-Gaza Faculty of Pharmacy, Department of Chemistry and Pharmaceutical Chemistry, Gaza, Palestine.ORCID 0000-0002-8934-2191
Hanan Mohammed FayyadAl-Azhar University-Gaza Faculty of Pharmacy, Department of Chemistry and Pharmaceutical Chemistry, Gaza, Palestine.ORCID 0000-0002-0898-1363
Ahmed Fadel ElqedraAl-Azhar University-Gaza Faculty of Pharmacy, Department of Chemistry and Pharmaceutical Chemistry, Gaza, Palestine.ORCID 0000-0001-6387-917X
Mai Abed Alrahman RamadanAl-Azhar University-Gaza Faculty of Pharmacy, Department of Pharmaceutics and Industrial Pharmacy, Gaza, Palestine.ORCID 0000-0001-8032-5777
Ihab Mustafa AlmasriAl-Azhar University-Gaza Faculty of Pharmacy, Department of Pharmaceutics and Industrial Pharmacy, Gaza, Palestine.ORCID 0000-0001-5988-5059
Al-Azhar University – Gaza · PS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAcebutolol HCl (ABL) is a selective β-adrenergic receptor blocking agent that is preferably administered by the oral route despite its low bioavailability (30-50%). The purpose of this study was to evaluate the effect of verapamil HCl (VER) [as P-glycoprotein inhibitor (P-gp)] on the intestinal absorption of ABL by comparing the changes in the absorption rate constant (k MATERIALS AND

methods

resultsThe absorption study showed that k

conclusionThe results revealed that VER at a concentration of 400 μg/mL has a pronounced effect on the absorption kinetics of ABL (increased k

Indexed as

absorptionAcebutolol HClintestinal perfusion techniqueP-glycoproteinverapamil HCl

Identifiers

PMID33389978
PMCPMC7786063
OpenAlexW2997316077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.