ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022
Prognostic value of early left ventricular ejection fraction reserve during regadenoson stress solid-state SPECT-MPI.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Prognostic value of the left ventricular ejection fraction reserve acquired by gated myocardial perfusion SPECT in patients with CAD and reduced stress LVEF.Frontiers in cardiovascular medicine · 2024Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: single photon emission computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Developing a framework for evaluating and comparing risk models.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Is there room in the MPI toolbox for another prognostic indicator?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Quantitation of Poststress Change in Ventricular Morphology Improves Risk Stratification.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe hypothesized early post-stress left ventricular ejection fraction reserve (EFR) on solid-state-SPECT is associated with major cardiac adverse events (MACE).
methods151 patients (70 ± 12 years, male 50%) undergoing same-day rest/regadenoson stress
resultsDuring the follow-up (mean 3.2 years), 28 MACE occurred (19%). In Kaplan-Meier analysis, there was a significantly decreased event-free survival in patients with early EFR < 0% (P = 0.004). Similarly, there was a decreased event-free survival in patients with ∆ESV ≥ 5 ml at early stress (P = 0.003). However, EFR, ∆EDV, and ∆ESV at late stress were not associated with MACE-free survival. Cox proportional hazards model adjusting for clinical information and stress TPD demonstrated that EFR, ∆EDV, and ∆ESV at early stress were significantly associated with MACE (P < 0.05 for all).
conclusionsReduced early post-stress EFR on vasodilator stress solid-state SPECT is associated with MACE.
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Registered trials
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