Evidence map›Paper›PMID 33389421›Full record

ArticleJournal of community health2021

COVID-19 Vaccination Hesitancy in the United States: A Rapid National Assessment.

Jagdish Khubchandani, Sushil Sharma, James H Price, Michael J Wiblishauser, Manoj Sharma, Fern J Webb

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Journal of community health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 650 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
650citing papers in PubMed, 4 pooled it
127.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04865029 phase2terminatednot on this map

Acute Estradiol and Progesterone Therapy in Hospitalized Adults to Reduce Coronavirus Disease (COVID-19) Severity: A Randomized Control Trial

TypeinterventionalSponsorTulane UniversityRan2021 to 2022Enrolled10ConditionsCovid19ArmsPlacebo injection and placebo pill, Estradiol Cypionate 5 mg/ml, Progesterone 200 mg Oral Capsule
NCT05084976 completednot on this map

Parental Perception of COVID-19 Vaccine in Pediatric Patients With Tracheostomy and Ventilator Dependence

TypeobservationalSponsorNorthwell HealthRan2021 to 2022Enrolled60ConditionsChronic Respiratory Failure, Tracheostomy Complication, Mechanical Ventilation ComplicationArmsCOVID 19 vaccine counseling
3 · Its place in the literature

Who cites it

650 citing papers in PubMed, 4 syntheses or guidelines pooled it, 1,130 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Using the Diffusion of Innovation Theory to Understand COVID-19 Booster Hesitancy in Adults.International journal of environmental research and public health · 2026
    Article
  12. Vaccine uptake and hesitancy among Black people: A scoping review.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

590 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Jagdish KhubchandaniDepartment of Public Health Sciences, New Mexico State University, Las Cruces, NM, 88003, USA. jagdish@nmsu.edu.
Sushil SharmaMiller College of Business, Ball State University, Muncie, IN, 47306, USA.
James H PriceDepartment of Population Health, Emeritus Professor of Public Health, University of Toledo, Toledo, OH, 43606, USA.
Michael J WiblishauserDepartment of Health Studies, University of Houston-Victoria, Victoria, TX, 77901, USA.
Manoj SharmaDepartment of Environmental & Occupational Health, University of Nevada, Las Vegas, NV, 89119, USA.
Fern J WebbDepartment of Community Health and Family Medicine, University of Florida, Jacksonville, FL, 32209, USA.
Miller College · USNew Mexico State University · USUniversity of Florida Health · USUniversity of Houston - Victoria · USUniversity of Nevada, Las Vegas · USUniversity of Toledo · US

Funding

Understanding Obesity In Relation to the Built EnvironmentP20MD006899 · NIMHD · JACKSON STATE UNIVERSITY · PI ANTOINE-LAVIGNE, DONNA A · 2012 to 2016
$5.3M
NIMHD NIH HHS P20 MD006899
6 · The paper itself

Abstract

Given the results from early trials, COVID-19 vaccines will be available by 2021. However, little is known about what Americans think of getting immunized with a COVID-19 vaccine. Thus, the purpose of this study was to conduct a comprehensive and systematic national assessment of COVID-19 vaccine hesitancy in a community-based sample of the American adult population. A multi-item valid and reliable questionnaire was deployed online via mTurk and social media sites to recruit U.S. adults from the general population. A total of 1878 individuals participated in the study where the majority were: females (52%), Whites (74%), non-Hispanic (81%), married (56%), employed full time (68%), and with a bachelor's degree or higher (77%). The likelihood of getting a COVID-19 immunization in the study population was: very likely (52%), somewhat likely (27%), not likely (15%), definitely not (7%), with individuals who had lower education, income, or perceived threat of getting infected being more likely to report that they were not likely/definitely not going to get COVID-19 vaccine (i.e., vaccine hesitancy). In unadjusted group comparisons, compared to their counterparts, vaccine hesitancy was higher among African-Americans (34%), Hispanics (29%), those who had children at home (25%), rural dwellers (29%), people in the northeastern U.S. (25%), and those who identified as Republicans (29%). In multiple regression analyses, vaccine hesitancy was predicted significantly by sex, education, employment, income, having children at home, political affiliation, and the perceived threat of getting infected with COVID-19 in the next 1 year. Given the high prevalence of COVID-19 vaccine hesitancy, evidence-based communication, mass media strategies, and policy measures will have to be implemented across the U.S. to convert vaccines into vaccinations and mass immunization with special attention to the groups identified in this study.

Indexed as

AdultCOVID-19COVID-19 VaccinesFemaleHumansMalePatient Acceptance of Health CarePatient ComplianceSurveys and QuestionnairesUnited StatesVaccinationVaccination RefusalCOVID-19 VaccinesCOVID-19InfectionPandemicPreventionPublic healthVaccine

Identifiers

PMID33389421
PMCPMC7778842
OpenAlexW3119136666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.