Evidence map›Paper›PMID 33389253›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021

Neuroimaging in idiopathic adult-onset focal dystonia.

Giovanni Fabbrini, Antonella Conte, Gina Ferrazzano, Marcello Esposito, Alberto Albanese, Roberta Pellicciari, Francesca Di Biasio, Francesco Bono, Roberto Eleopra, Tommaso Ercoli and 4 more

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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Is Routine Neuroimaging Needed in Adult-Onset Isolated Cervical Dystonia?Tremor and other hyperkinetic movements (New York, N.Y.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 1 country.

Giovanni FabbriniDepartment of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, 00185, Rome, Italy. Giovanni.fabbrini@uniroma1.it.ORCID http://orcid.org/0000-0001-7614-8771
Antonella ConteDepartment of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, 00185, Rome, Italy.
Gina FerrazzanoDepartment of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, 00185, Rome, Italy.
Marcello EspositoClinical Neurophysiology Unit "Esposito Marcello", Cardarelli Hospital, Naples, Italy.
Alberto AlbaneseDepartment of Neurology, IRCCS, Humanitas Research Hospital, Rozzano, Milan, Italy.
Roberta PellicciariDepartment of Basic Science, Neuroscience, and Sense Organs, Aldo Moro University of Bari, Bari, Italy.
Francesca Di BiasioSan Martino Polyclinic Hospital IRCCS, Genoa, Italy.
Francesco BonoBotulinum Toxin Center, Neurology Unit A.O.U. Mater domini, Catanzaro, Italy.
Roberto EleopraParkinson and Movement Disorders Unit, IRCCS Foundation, Neurology Institute "Carlo Besta", Milan, Italy.
Tommaso ErcoliDepartment of Medical Science and Public Health, Institute of Neurology, University of Cagliari, Cagliari, Italy.
Maria Concetta AltavistaNeurology Unit, San Filippo Neri Hospital ASL Roma 1, Rome, Italy.
Alfredo BerardelliDepartment of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, 00185, Rome, Italy.
Giovanni DefazioDepartment of Medical Science and Public Health, Institute of Neurology, University of Cagliari, Cagliari, Italy.
Italian Dystonia Registry participants
Istituto Neurologico Mediterraneo · ITUniversity of Cagliari · ITASL Roma · ITAzienda Ospedaliero Universitario Mater Domini · ITFondazione IRCCS Istituto Neurologico Carlo Besta · ITIRCCS Humanitas Research Hospital · ITOspedale Antonio Cardarelli · ITOspedale Policlinico San Martino · ITSapienza University of Rome · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to study the attitude of Italian neurologists in the use of conventional MRI in patients with idiopathic adult-onset focal dystonia. Patients were included in the Italian Dystonia Registry by experts working in different Italian centers. MRI was available for 1045 of the 1471 (71%) patients included in the analysis. Using logistic regression analysis, we found that MRI was more likely to be performed in patients with cervical dystonia, spasmodic dysphonia, or non-task-specific upper limb dystonia, whereas it was less likely to be performed in patients with blepharospasm or task-specific upper limb dystonia. We did not find differences in the number of MRIs performed between neurological centers in Northern, Central, and Southern Italy. We conclude that although the diagnosis of idiopathic adult-onset dystonia is mainly based on clinical grounds, many movement disorder experts rely on MRI to confirm a diagnosis of idiopathic dystonia. We suggest that neuroimaging should be used in patients with adult-onset focal dystonia to rule out secondary forms.

Indexed as

BlepharospasmDystonic DisordersTorticollisAdultHumansItalyNeuroimagingArm dystoniaBlepharospasmCervical dystoniaLaryngeal dystoniaMagnetic resonance imaging

Identifiers

PMID33389253
OpenAlexW3120243350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.