Evidence map›Paper›PMID 33389221›Full record

ArticleTropical animal health and production2021

Differential gene expression in duodenum of colored broiler chicken divergently selected for residual feed intake.

Prakash Anand, Saxena Vishesh Kumar, Kumar Ravi, Tomar Simmi

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Article in Tropical animal health and production, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Prakash AnandDepartment of Livestock Farm Complex, College of Veterinary Science, Rampura Phul, GADVASU, Ludhiana, India. anandprakash0412@gmail.com.ORCID https://orcid.org/0000-0001-8049-8184
Saxena Vishesh KumarDivision of Avian Genetics and Breeding, Central Avian Research Institute, Indian Council of Agricultural Research, Bareilly (Uttar Pradesh), India.
Kumar RaviNational institute of animal biotechnology, Hyderabad, Telangana, India.
Tomar SimmiDivision of Avian Genetics and Breeding, Central Avian Research Institute, Indian Council of Agricultural Research, Bareilly (Uttar Pradesh), India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feed constitutes about 70% of the total expenditure of poultry production. Maximizing the feed efficiency in juvenile period is essential to achieve low production cost. The efficiency of feed utilization was measured by RFI (residual feed intake) by calculating the difference between an individual animal's observed and its expected feed intake. The expression of genes influencing low and high RFI is required to know the basic molecular mechanism influencing feed efficiency. The present study aimed to estimate the RFI (0-5 week) in a population of indigenously developed colored broiler sire line chicken. The duodenum sample of high and low-RFI broiler chicken was used for microarray analysis. Duodenum exhibited 1030 differentially expressed genes after analysis. Out of total DEGs, 461 genes were downregulated and 569 were upregulated. The fold change of differentiallly expressed genes varies from - 162.6 to 1549.28. A subset of genes was validated by qRT-PCR and results were correlated well with microarray data. In functional annotation study of DEGs, 89 biological processes, 30 cellular components, and 29 molecular functions were identified. Study of the important differentially expressed genes and the related molecular pathways in the population may hold the potential for future breeding strategies for augmenting feed efficiency.

Indexed as

TranscriptomeAnimalsBreedingChickensDuodenumEatingFemaleGene ExpressionGene Expression ProfilingMalePhenotypePoultry ProductsProtein Interaction MapsSelective BreedingDifferential gene expressionFeed efficiencyMicroarrayResidual feed intake

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.