ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021
Impact of mechanical stability on the progress of bone ongrowth on the frame surfaces of a titanium-coated PEEK cage and a 3D porous titanium alloy cage: in vivo analysis using CT color mapping.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 17 citations in OpenAlex.
- Graphene oxide-modified PEEK composites: Properties and applications in orthopaedic repair - A review.Journal of orthopaedic translation · 2026Review
- Evaluation of bony fusion after posterior lumbar interbody fusion: a systematic review and meta-analysis.Brain & spine · 2026Review
- Evolution of Titanium Interbody Cages and Current Uses of 3D Printed Titanium in Spine Fusion Surgery.Current reviews in musculoskeletal medicine · 2025Review
- Innovative 3D-printed porous tantalum cage with non-window design to accelerate spinal fusion: A proof-of-concept study.Materials today. Bio · 2025Article
- Biomechanical design of titanium-PEEK combined fusion cage based on PLIF surgical model.Frontiers in bioengineering and biotechnology · 2025Article
- The Biocompatibility and the Effect of Titanium and PEKK on the Osseointegration of Customized Facial Implants.Materials (Basel, Switzerland) · 2024Article
- Fundamentals of Mechanobiology and Potential Applications in Spinal Fusion.International journal of spine surgery · 2023Article
- Effect of Interbody Implants on the Biomechanical Behavior of Lateral Lumbar Interbody Fusion: A Finite Element Study.Journal of functional biomaterials · 2023Article
- Can activated titanium interbody cages accelerate or enhance spinal fusion? a review of the literature and a design for clinical trials.Journal of materials science. Materials in medicine · 2021Review
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5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the impact of mechanical stability on the progress of bone ongrowth on the frame surfaces of a titanium-coated polyether ether ketone (TCP) cage and a three-dimensional porous titanium alloy (PTA) cage following posterior lumbar interbody fusion (PLIF) until 1 year postoperatively.
methodsA total of 59 patients who underwent one- or two-level PLIF for degenerative lumbar disorders since March 2015 were enrolled. Bone ongrowth of all cage frame surfaces (four surfaces per cage: TCP, 288 surfaces and PTA, 284 surfaces) was graded by 6-month and 1-year postoperative computed tomography color mapping (grade 0, 0‒25% of bone ongrowth; grade 1, 26‒50%; grade 2, 51‒75%; and grade 3, 76‒100%).
resultsBone ongrowth (≥ grade 1) was observed on 58.0% and 69.0% of the surfaces of TCP and PTA cages 6 months postoperatively and on 63.5% and 75.0% of those 1 year postoperatively, respectively. In the TCP cages, bone ongrowth grade increased from 6 months to 1 year postoperatively only in the union segments (median, 1 [interquartile range, IQR, 0-2] to 1 [IQR, 0-3], p = 0.006). By contrast, in the PTA cages, it increased at 6 months postoperatively in the union (1 [IQR, 1-2] to 2 [IQR, 1-3], p = 0.003) and non-union (0.5 [IQR, 0-2] to 1 [IQR, 0-2.75], p = 0.002) segments.
conclusionEarly postoperative mechanical stability has a positive impact on the progress of bone ongrowth on both the TCP and PTA cage frame surfaces after PLIF.
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