Evidence map›Paper›PMID 33389115›Full record

Observational studyLangenbeck's archives of surgery2021

Jaundice as a clinical presentation in liver hydatidosis increases the risk of postoperative biliary fistula.

Isabel Jaén-Torrejimeno, Raquel Latorre-Fragua, Diego López-Guerra, Adela Rojas-Holguín, Alba Manuel-Vázquez, Gerardo Blanco-Fernández, José Manuel Ramia

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Langenbeck's archives of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05113550 (Surgical Treatment of Hepatic Hydatidosis in Elderly Patients), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05113550 completednot on this map

Surgical Treatment of Hepatic Hydatidosis in Elderly Patients

TypeobservationalSponsorUniversidad de ExtremaduraRan2021 to 2021Enrolled279ConditionsCystic EchinococcosisArmsSurgical remove
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Isabel Jaén-TorrejimenoDepartment of HBP and Liver Transplant Surgery, University Hospital Complex Badajoz, University of Extremadura, Avda de Elvas s/n, 06080, Badajoz, Spain.ORCID https://orcid.org/0000-0001-6616-4807
Raquel Latorre-FraguaDepartment of HBP, General and Digestive Surgery, University Hospital of Guadalajara, Guadalajara, Spain.
Diego López-GuerraDepartment of HBP and Liver Transplant Surgery, University Hospital Complex Badajoz, University of Extremadura, Avda de Elvas s/n, 06080, Badajoz, Spain.
Adela Rojas-HolguínDepartment of HBP and Liver Transplant Surgery, University Hospital Complex Badajoz, University of Extremadura, Avda de Elvas s/n, 06080, Badajoz, Spain.
Alba Manuel-VázquezDepartment of HBP, General and Digestive Surgery, University Hospital of Guadalajara, Guadalajara, Spain.
Gerardo Blanco-FernándezDepartment of HBP and Liver Transplant Surgery, University Hospital Complex Badajoz, University of Extremadura, Avda de Elvas s/n, 06080, Badajoz, Spain. gerardoblanco@unex.es.ORCID http://orcid.org/0000-0003-4845-5306
José Manuel RamiaDepartment of HBP, General and Digestive Surgery, University Hospital of Alicante, Alicante, Spain.
Universidad de Extremadura · ESHospital Universitario de Guadalajara · ESGovernment of Extremadura · ESHospital General Universitario de Alicante Doctor Balmis · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEchinococcosis, also known as hydatidosis, is a zoonosis that is endemic in many countries worldwide. Liver hydatid cysts have a wide variety of clinical manifestations, among which obstructive jaundice is one of the rarer forms. The aims of the study were to analyze the preoperative management of these patients and to record the kind of surgical treatment performed and the short- and long-term postoperative results.

methodsA retrospective two-center observational study of patients operated upon for liver hydatidosis with initial symptoms of obstructive jaundice. Preoperative characteristics, surgical data, and postoperative complications, including biliary fistula, were recorded.

resultsOf 353 patients operated upon for liver hydatidosis, 44 were included in the study. Thirty-five patients (79.6%) were defined as CE2 or CE3 in the World Health Organization (WHO) classification. Preoperative endoscopic retrograde cholangiopancreatography (ERCP) was performed in 25 patients (56.8%) and identified intrabiliary communication in 29. Radical surgery was carried out in 29 of the total sample (65.9%). Severe postoperative complications (Clavien-Dindo grade IIIA or higher) were recorded in 25% of patients. The factors associated with greater postoperative morbidity were age above 65 (HR 8.76 [95% CI 0.78-97.85]), cyst location (HR 4.77 [95% CI 0.93-24.42]), multiple cysts (HR 14.58 [95% CI 1.42-149.96]), and cyst size greater than 5 cm (HR 6.88 [95% CI 0.95-50]).

conclusionThe presentation as obstructive jaundice causes greater postoperative morbidity. The main postoperative complication in these cases, despite radical surgery, is biliary fistula. In our series, routine preoperative ERCP did not show any benefit.

Indexed as

Biliary FistulaEchinococcosisJaundiceCholangiopancreatography, Endoscopic RetrogradeHumansLiverPostoperative ComplicationsRetrospective StudiesCystobiliary communicationERCPJaundiceLiver hydatid cyst

Identifiers

PMID33389115
OpenAlexW3118743411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.