Evidence map›Paper›PMID 33389039›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2021

Aortic valve replacement in Germany in 2019.

Luise Gaede, Johannes Blumenstein, Oliver Husser, Christoph Liebetrau, Oliver Dörr, Christina Grothusen, Clemens Eckel, Hani Al-Terki, Won-Keun Kim, Holger Nef and 5 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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  6. Transcatheter-based aortic valve replacement vs. isolated surgical aortic valve replacement in 2020.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Luise GaedeMedizinische Klinik 2, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland.
Johannes BlumensteinDepartment of Internal Medicine, Medizinische Klinik 1, St. Johannes-Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany.
Oliver HusserDepartment of Internal Medicine, Medizinische Klinik 1, St. Johannes-Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany.
Christoph LiebetrauCCB Frankfurt, Frankfurt, Germany.
Oliver DörrMedical Clinic I, Department of Cardiology and Angiology, University of Giessen, Giessen, Germany.
Christina GrothusenDepartment of Internal Medicine, Medizinische Klinik 1, St. Johannes-Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany.
Clemens EckelDepartment of Internal Medicine, Medizinische Klinik 1, St. Johannes-Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany.
Hani Al-TerkiDepartment of Internal Medicine, Medizinische Klinik 1, St. Johannes-Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany.
Won-Keun KimDepartment of Cardiology, Kerckhoff Heart and Thorax Center, Bad Nauheim, Germany.
Holger NefMedical Clinic I, Department of Cardiology and Angiology, University of Giessen, Giessen, Germany.
Christian TescheDepartment of Internal Medicine, Medizinische Klinik 1, St. Johannes-Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany.
Christian W HammMedical Clinic I, Department of Cardiology and Angiology, University of Giessen, Giessen, Germany.
Albrecht ElsässerCarl Von Ossietzky Universität Oldenburg, Oldenburg, Germany.
Stephan AchenbachMedizinische Klinik 2, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland.
Helge MöllmannDepartment of Internal Medicine, Medizinische Klinik 1, St. Johannes-Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany. moellmann@me.com.ORCID http://orcid.org/0000-0002-6047-0990
St.-Johannes-Hospital Dortmund · DEJustus-Liebig-Universität Gießen · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DECardiovascular Center Bethanien · DECarl von Ossietzky Universität Oldenburg · DEKerckhoff Klinik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsBoth surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI) are established options to treat aortic valve stenosis. We present the outcome of the complete cohort of all patients undergoing SAVR or TAVI in Germany during the calendar year 2019. METHODS AND

resultsData concerning all isolated aortic valve procedures performed in Germany in 2019 were retrieved from the mandatory nationwide quality control program: 22,973 transvascular (TV)-TAVI procedures, 7905 isolated SAVR (iSAVR), and 1413 transapical (TA)-TAVI. Data was complete in 99.9% (n = 32,156). In-hospital mortality after TV-TAVI (2.3%) was significantly lower when compared with iSAVR (2.8%, p = 0.007) or TA-TAVI (6.3%; p < 0.001). Expected mortality was calculated with a new version of the German Aortic valve score (AKL Score) based on the data of either catheter-based (AKL-CATH) or surgical (AKL-CHIR) aortic valve replacements in Germany in 2018. TV-TAVI and iSAVR both showed lower observed mortality in 2019 than expected based on their respective performance in 2018, yielding an observed/expected (O/E) mortality ratio < 1. This was particularly apparent for patients at low risk. After exclusion of emergency procedures, in-hospital mortality after TV-TAVI (2.1%) and after iSAVR (2.1%) was identical, even though patients undergoing TV-TAVI showed a considerably higher perioperative risk profile.

conclusionAfter excluding emergency procedures, in-hospital mortality of TV-TAVI and iSAVR in 2019 in Germany was identical. In 2019, TV-TAVI and iSAVR both show lower matched mortality ratios compared with 2018, which suggests technical improvements of both therapies.

Indexed as

AgedAged, 80 and overAortic ValveAortic Valve StenosisFemaleFollow-Up StudiesGermanyHumansIncidenceMaleRetrospective StudiesTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeMortalityReal worldRegistrySAVRTAVITAVR

Identifiers

PMID33389039
OpenAlexW3120272265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.