Evidence map›Paper›PMID 33388988›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

The efficacy of sphenopalatine ganglion block for pain management after endoscopic sinus surgery: a meta-analysis of randomized controlled studies.

Ping Wang

2 registry-linked trialsAbstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06353529 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Sphenopalatine Ganglion Block With Bupivacaine on Postoperative Pain in Patients Undergoing Endoscopic Pituitary Adenoma Resection

TypeinterventionalSponsorHamilton Health Sciences CorporationRan2024 to 2026Enrolled108ConditionsPituitary, Pain, PostoperativeArmsBupivacaine-Epinephrine 0.5%-1:200,000 Injectable Solution, Placebo, Sham Comparator
NCT07645521 nacompletednot on this mapstarted 2025, after this paper: background citation

Effect of Bilateral Trans-nasal Sphenopalatine Ganglion Block on Emergence Agitation Following Functional Endoscopic Sinus Surgery: A Double-Blind Randomized Controlled Trial

TypeinterventionalSponsorMansoura UniversityRan2025 to 2026Enrolled100ConditionsChronic Rhinosinusitis (CRS), Emergence AgitationArmsBilateral Trans-nasal Sphenopalatine Ganglion Block, Sham Trans-nasal Injection
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ping WangOtolaryngology Department, The First People's Hospital of Chongqing Liangjiang New Areas, No. 199, Renxing Road, Renhe Street, Chongqing, 401121, China. 843255985@qq.com.ORCID http://orcid.org/0000-0002-7114-3741
First People's Hospital of Chongqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe efficacy of sphenopalatine ganglion (SPG) block for pain control after endoscopic sinus surgery remains controversial. We conduct a systematic review and meta-analysis to explore the influence of SPG block on pain intensity after endoscopic sinus surgery.

methodsWe search PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through June 2019 for randomized controlled trials (RCTs) assessing the efficacy of SPG block for pain management after endoscopic sinus surgery. This meta-analysis is performed using the random-effect model.

resultsSix RCTs are included in the meta-analysis. Overall, compared with control group for endoscopic sinus surgery, SPG block is associated with the decrease in pain scores at 6 h (Std. MD =  - 0.71; 95% CI =  - 1.08 to - 0.34; P = 0.0002) and 24 h (Std. MD =  - 0.51; 95% CI =  - 0.87 to - 0.14; P = 0.006), the number of rescue analgesics (RR = 0.26; 95% CI = 0.16 to 0.42; P < 0.00001) and incidence of nausea and vomiting (RR = 0.52; 95% CI = 0.30-0.89; P = 0.02), but demonstrate no obvious impact on pain scores at 2 h (Std. MD =  - 0.99; 95% CI =  - 2.80-0.83; P = 0.29) or headache (RR = 1.30; 95% CI = 0.38-4.46; P = 0.67).

conclusionsSPG block can provide additional benefits for pain management after endoscopic sinus surgery.

Indexed as

Pain ManagementSphenopalatine Ganglion BlockAnalgesicsEndoscopyHumansPostoperative PainRandomized Controlled Trials as TopicAnalgesicsEndoscopic sinus surgeryPain managementRandomized controlled trialsSphenopalatine ganglion (SPG) block

Identifiers

PMID33388988
OpenAlexW3120936038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.