Evidence map›Paper›PMID 33388973›Full record

SynthesisLung2021

Uniportal Versus Multiportal Video-Assisted Thoracoscopic Lobectomy for Lung Cancer: An Updated Meta-analysis.

Dimitrios E Magouliotis, Maria P Fergadi, Kyriakos Spiliopoulos, Kalliopi Athanassiadi

Erratum issuedAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Lung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Single-Port Robotic-Assisted Approach in Thoracic Surgery: A Prospective Real-World Study.Interdisciplinary cardiovascular and thoracic surgery · 2025
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  16. Initial outcomes with uniportal video-assisted lung resection.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Dimitrios E MagouliotisDivision of Surgery and Interventional Science, Faculty of Medical Sciences, UCL, London, UK. dimitrios.magouliotis.18@ucl.ac.uk.ORCID http://orcid.org/0000-0001-5417-6392
Maria P FergadiFaculty of Medicine, University of Thessaly, Biopolis, Larissa, Greece.
Kyriakos SpiliopoulosDepartment of Thoracic and Cardiovascular Surgery, Larissa University Hospital, Larissa, Greece.
Kalliopi AthanassiadiUnit of Thoracic Surgery, Evangelismos Hospital, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe reviewed the available literature on patients with lung cancer undergoing either uniportal (UVATS) or multiport video-assisted thoracoscopic surgery (MVATS).

methodsOriginal research studies that evaluated perioperative and long-term outcomes of UVATS versus MVATS were identified, from January 1990 to April 2020. The perioperative, along with the oncologic and long-term survival outcomes, were calculated according to either a fixed or a random effect model, appropriately. The Q statistics and I

resultsTwenty studies were included, incorporating a total of 1,469 patients treated with UVATS and 3,231 treated with MVATS. The incidence of complications was lower in patients treated with UVATS [OR: 0.76 (95% CI 0.62, 0.93); p = 0.008]. The chest tube duration was significantly lower in the UVATS group (WMD: - 0.63 [95% CI - 1.03, - 0.23]; p = 0.002). Length of hospital stay (L.O.S.) was also lower in the UVATS patient group (WMD: - 0.54 [- 0.94, - 0.13]; p = 0.009), along with postoperative pain [WMD: - 0.57 (95% CI - 0.97, - 0.18); p = 0.004]. No significant differences were found regarding the mean operative time (M.O.T.), mean blood loss, the number of resected lymph nodes, the 30-day mortality, along with the survival at 1 and 3 years postoperatively.

conclusionsThe present meta-analysis indicates that UVATS is associated with enhanced outcomes in patients undergoing surgery for lung cancer. Well-designed, randomized studies, comparing UVATS to MVATS, are necessary to further assess their long-term clinical outcomes.

Indexed as

HumansLength of StayLung NeoplasmsPneumonectomyPostoperative ComplicationsThoracic Surgery, Video-AssistedLung cancerSingle incisionUniportalUvatsVatsVideo-assisted thoracoscopic surgery

Identifiers

PMID33388973
PMCPMC7929953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.