Evidence map›Paper›PMID 33388955›Full record

ArticlePediatric surgery international2021

Morbidity after thoracoscopic resection of congenital pulmonary airway malformations (CPAM): single center experience over a decade.

Hadiya Khan, Meera Kurup, Sanjay Saikia, Ashish Desai, Malcolm Mathew, Asme Sheikh, Chulananda D A Goonasekera

Registry-linked trialAbstract read
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In one paragraph

Article in Pediatric surgery international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04449614 (A Review of Surgical Management of Congenital Pulmonary Airway Malformations), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04449614 completednot on this map

A Review of Surgical Management of Congenital Pulmonary Airway Malformations (CPAM): A Decade of Experience

TypeobservationalSponsorKing's College Hospital NHS TrustRan2018 to 2020Enrolled72ConditionsPulmonary Arteriovenous Malformation, Congenital DisordersArmsThoracoscopic CPAM resection
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hadiya KhanRoyal Surrey County Hospital, Guildford, GU2 7XX, UK.
Meera KurupDepartment of Anesthetics, Kings College Hospital, Denmark Hill, London, SE5 9RS, UK.
Sanjay SaikiaDepartment of Anesthetics, Kings College Hospital, Denmark Hill, London, SE5 9RS, UK.
Ashish DesaiConsultant Paediatric Surgeon, Royal London Hospital, London, E11FR, UK.
Malcolm MathewDepartment of Anesthetics, Kings College Hospital, Denmark Hill, London, SE5 9RS, UK.
Asme SheikhDepartment of Anesthetics, Kings College Hospital, Denmark Hill, London, SE5 9RS, UK.
Chulananda D A GoonasekeraDepartment of Anesthetics, Kings College Hospital, Denmark Hill, London, SE5 9RS, UK. chula.goonasekera@nhs.net.ORCID http://orcid.org/0000-0002-9754-6477
King's College Hospital · GBRoyal London Hospital · GBRoyal Surrey County Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVideo-assisted thoracoscopic (VATS) resection of CPAM in children is an established, albeit controversial strategy for its management. We report a 10-year single center experience.

methodsAll children underwent VATS (2008-2017) and their current status was reviewed. Patients were grouped: 'symptomatic-P' (if parents reported recurrent lower respiratory tract infections etc.) or 'symptomatic-S' (neonates presenting with respiratory distress/difficulty) or 'asymptomatic'.

results73 children, aged 10 m (4d-14yrs) underwent VATS; a neonate as an emergency ('symptomatic-S') and all others electively. The lesion was unilateral in all but one case. Histologically none were malignant. Of the elective 72 cases, 7 (10%) required conversion to open thoracotomy. Twenty (27.7%) were 'symptomatic-P' and the duration of surgery when compared to 'asymptomatic' children was longer 269 (range 129-689) versus 178 (range 69-575) minutes (P = 0.01). Post operatively, 8 children (11%) had a grade III/IV (Clavien-Dindo) complication; persistent air leak/pneumothorax (n = 5), chylothorax (n = 1), pleural effusion (n = 1) and seizure/middle cerebral artery thrombosis (n = 1). There was no mortality. Twenty-four children (33.3%) were reported 'symptomatic-P' post-surgery after a median follow up of 2.18 years. The surgical intervention had no impact on 'symptomatic-P' status (P = 0.46).

conclusionThe risks of surgery may outweigh benefit in asymptomatic children. CLINICALTRIALS. GOV IDENTIFIER: NCT04449614.

Indexed as

AdolescentChildChild, PreschoolCystic Adenomatoid Malformation of Lung, CongenitalFemaleHumansInfantInfant, NewbornMaleMorbidityPneumothoraxPostoperative PeriodRetrospective StudiesThoracic Surgery, Video-AssistedThoracoscopyThoracotomyChildrenComplicationsCongenital pulmonary airway malformationsInfantsOutcomesThoracic surgery video-assisted

Identifiers

PMID33388955
OpenAlexW3120791098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.