ArticleArchives of orthopaedic and trauma surgery2021
Short-term mortality after primary and revision total joint arthroplasty: a single-center analysis of 103,560 patients.
Article in Archives of orthopaedic and trauma surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Periprosthetic joint infection as the leading indication associated with in-hospital death after revision hip and knee arthroplasty: a ten-year single-centre retrospective cohort study of 103 in-hospital deaths among 2495 patients.Journal of orthopaedic surgery and research · 2026Article
- A survey of Scottish Committee for Orthopaedics and Trauma members on lower limb joint replacement practices in morbidly obese patients.Journal of clinical orthopaedics and trauma · 2025Article
- Cause of death following revision for periprosthetic joint infection or major aseptic revision in total hip and knee arthroplasty.Journal of bone and joint infection · 2025Article
- Does addition of gentamicin for antibiotic prophylaxis in total knee arthroplasty reduce the rate of periprosthetic joint infection?Archives of orthopaedic and trauma surgery · 2023Article
- Medial proximal tibial resorption after total knee arthroplasty according to the design of the cobalt chrome tibial baseplate.Archives of orthopaedic and trauma surgery · 2023Article
- Long-term cost-effectiveness of matrix-associated chondrocyte implantation in the German health care system: a discrete event simulation.Archives of orthopaedic and trauma surgery · 2023Article
- Risk factors for mortality following one-stage septic hip arthroplasty - a case-control study.International orthopaedics · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe demand for total joint arthroplasty (TJA) is increasing worldwide with excellent long-term results. In general, TJA provides several benefits to the patients but also causes possible complications. The aim of our study was to describe trends in mortality after TJA in a high-volume arthroplasty center, and to examine the potential risk factors.
methodsFrom 1996 to 2018, a total of 103,560 patients (73,130 primary cases, 30,430 revision cases) underwent a TJA procedure in our institution. Anthropometric parameters, Charlson Comorbidity Index (CCI), pre- and postoperative hemoglobin (Hb), blood loss during surgery, postoperative complication (such as infection, deep vein thrombosis, pulmonary embolism, etc.) and cause of death from all patients who deceased during hospitalization were collected. The short-term mortality rate was analyzed between the primary and the revision groups.
resultsThe short-term mortality rate within our investigated groups was low with 0.041% in primary THA, 0.299% in revision THA, 0.045% in primary TKA, 0.205% in revision TKA, 0.214% in TSA/RSA, 0.15 % in primary TAA and 0% after TEA. Significant differences were found for preoperative Hb-values in patients undergoing septic revision (10.7 g/dl) compared to patients undergoing aseptic revision (12.8 g/dl) or primary arthroplasty (13.6 g/dl) (p < 0.001). Furthermore, we found significant differences regarding CCI between the groups. The comparison between causes of death (COD) showed a significantly higher number for pulmonary embolisms in the aseptic groups, while septic shock was the leading COD in the septic group and myocardial infarction as COD was found significantly more often after primary TJA.
conclusionThis is the largest single-center study presenting the short-term mortality rate following TJA. Consequently, TJA is a safe procedure with a low short-term mortality rate. However, depending on the type of surgery, certain risk factors cannot be eliminated. In order to further reduce the mortality, procedures as such should continue to be performed at specialized centers under standardized conditions.
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