Evidence map›Paper›PMID 33388850›Full record

ReviewPediatric cardiology2021

Loss of Consciousness in the Young Child.

Juan Villafane, Jacob R Miller, Julie Glickstein, Jonathan N Johnson, Jonathan Wagner, Chris S Snyder, Tatiana Filina, Scott L Pomeroy, S Kristen Sexson-Tejtel, Caitlin Haxel and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. A framework to simplify paediatric syncope diagnosis.European journal of pediatrics · 2023
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Juan VillafaneDepartment of Pediatrics, University of Cincinnati and Cincinnati Children's Hospital, Cincinnati, OH, USA. juan.villafane@cchmc.org.
Jacob R MillerDepartment of Surgery, Division of Cardiothoracic Surgery, St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, MO, USA.
Julie GlicksteinDepartment of Pediatrics, Columbia University Medical Center, New York-Presbyterian Hospital, New York, NY, USA.
Jonathan N JohnsonDepartment of Pediatric and Adolescent Medicine, Division of Pediatric Cardiology, Mayo Clinic, Rochester, MN, USA.
Jonathan WagnerDepartment of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.
Chris S SnyderCongenital Heart Collaborative, Rainbow Babies and Children's Hospital, Case Western University, Cleveland, OH, USA.
Tatiana FilinaDepartment of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Scott L PomeroyDepartment of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
S Kristen Sexson-TejtelDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Caitlin HaxelDepartment of Pediatrics, Children's Hospital of Colorado, University of Colorado School of Medicine, Aurora, CO, USA.
Jason GottliebLancaster Pediatric Associates, Lancaster, PA, USA.
Pirooz EghtesadyDepartment of Surgery, Division of Cardiothoracic Surgery, St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, MO, USA.
Devyani ChowdhuryCardiology Care for Children, Lancaster, PA, USA.
Harvard University · USSt. Louis Children's Hospital · USBaylor College of Medicine · USCincinnati Children's Hospital Medical Center · USClinic for Special Children · USMayo Clinic in Florida · USNew York Hospital Queens · USRainbow Babies & Children's Hospital · USUniversity of Colorado Denver · USUniversity of Missouri–Kansas City · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the very young child (less than eight years of age), transient loss of consciousness represents a diagnostic and management dilemma for clinicians. While most commonly benign, syncope may be due to cardiac dysfunction which can be life-threatening. It can be secondary to an underlying ion channelopathy, cardiac inflammation, cardiac ischemia, congenital heart disease, cardiomyopathy, or pulmonary hypertension. Patients with genetic disorders require careful evaluation for a cardiac cause of syncope. Among the noncardiac causes, vasovagal syncope is the most common etiology. Breath-holding spells are commonly seen in this age group. Other causes of transient loss of consciousness include seizures, neurovascular pathology, head trauma, psychogenic pseudosyncope, and factitious disorder imposed on another and other forms of child abuse. A detailed social, present, past medical, and family medical history is important when evaluating loss of consciousness in the very young. Concerning characteristics of syncope include lack of prodromal symptoms, no preceding postural changes or occurring in a supine position, after exertion or a loud noise. A family history of sudden unexplained death, ion channelopathy, cardiomyopathy, or congenital deafness merits further evaluation. Due to inherent challenges in diagnosis at this age, often there is a lower threshold for referral to a specialist.

Indexed as

Arrhythmias, CardiacCardiomyopathiesChildChild, PreschoolDiagnosis, DifferentialHeart Defects, CongenitalHumansHypertension, PulmonaryMaleSeizuresSyncopeSyncope, VasovagalUnconsciousnessLoss of consciousnessPediatricSyncopeYoung child

Identifiers

PMID33388850
OpenAlexW3119098416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.