Evidence map›Paper›PMID 33388843›Full record

ArticleAnalytical and bioanalytical chemistry2021

Developing an integrated microfluidic and miniaturized electrochemical biosensor for point of care determination of glucose in human plasma samples.

Shamim Azimi, Ali Farahani, Aristides Docoslis, Sahar Vahdatifar

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Bacteria as living biosensors for DNA.Nature reviews bioengineering · 2026
    Article
  3. Article
  4. Article
  5. Machine-Learning-Aided Advanced Electrochemical Biosensors.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Shamim AzimiDepartment of Chemical Engineering, Queen's University, Kingston, ON, K7L 3N6, Canada.
Ali FarahaniNanobioelectronics Lab, School of Chemistry, College of Science, University of Tehran, Tehran, 1748714176, Iran. ali_farahani@ut.ac.ir.
Aristides DocoslisDepartment of Chemical Engineering, Queen's University, Kingston, ON, K7L 3N6, Canada.
Sahar VahdatifarDepartment of Chemical Engineering, Faculty of Engineering, University of Tehran, Tehran, 1438615995, Iran.
Queen's University · CAUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cost-effective, point of care (POC) device based on highly oriented CNT arrays was developed as an electrochemical assay for real-time and sensitive detection of glucose in complex samples. A low-cost, microcontroller-based potentiostat consisting of Arduino Due and LMP9100-EVM was developed to perform electrochemical measurements such as cyclic voltammetry (CV) and amperometry. A syringe pump based on open-source electronics was designed to direct the flow through a microfluidic chip. Vertically aligned carbon nanotube (VACNT) sensor arrays, in combination with the miniature potentiostat and the syringe pumps, were utilized as a POC device for the rapid and accurate detection of glucose. The structure and morphology of samples were characterized by field emission scanning electron microscopy (FESEM) and attenuated total reflectance Fourier transform infrared spectrometry (ATR-FTIR). CV as well as electrochemical impedance spectroscopy (EIS) was performed to investigate the electrochemical behavior of the electrode with respect to different diffusion regimes. The mediator-less biosensor had a limit of detection of 23 μM and sensitivity of 1462 μA mM

Indexed as

Biosensing TechniquesBlood GlucoseElectrochemical TechniquesElectrodesEquipment DesignHumansLimit of DetectionMicrofluidic Analytical TechniquesNanotubes, CarbonPoint-of-Care SystemsReproducibility of ResultsBlood GlucoseNanotubes, CarbonCyclic voltammetryElectrochemical biosensorMicrofluidic devicePoint of careVACNTs

Identifiers

PMID33388843
OpenAlexW3120816205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.