ArticleUltrasonics sonochemistry2021
Synergistic antibacterial and antibiofilm effects of ultrasound and MEL-A against methicillin-resistant Staphylococcus aureus.
Article in Ultrasonics sonochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 63 citations in OpenAlex.
- Biogenic Selenium Nanoparticles fromPharmaceutics · 2025Article
- Effects of combining lysozyme, ultrasound, and heat treatments on the inactivation of Bacillus subtilis spores.Archives of microbiology · 2025Article
- Proper NADES treatment improved Zanthoxylum bungeanum essential oil yield and boosted α-terpineol antibacterial efficacy.NPJ science of food · 2025Article
- Chlorogenic Acid: A Promising Strategy for Milk Preservation by InhibitingFoods (Basel, Switzerland) · 2024Article
- Antibacterial Activity of Phloretin AgainstFoods (Basel, Switzerland) · 2024Article
- Effects of Mannosylerythritol-Lipids-B onIndian journal of microbiology · 2024Article
- Antimicrobial and anti-biofilm activity of Polygonum chinense L.aqueous extract against Staphylococcus aureus.Scientific reports · 2022Article
- Synergistic Antibacterial Mechanism of Mannosylerythritol Lipid-A and Lactic Acid onFoods (Basel, Switzerland) · 2022Article
- Antibacterial mechanism of linalool emulsion against Pseudomonas aeruginosa and its application to cold fresh beef.World journal of microbiology & biotechnology · 2022Article
- Microwaves, a potential treatment for bacteria: A review.Frontiers in microbiology · 2022Review
- Ultrasonic-assisted preparation of eucalyptus oil nanoemulsion: Process optimization, in vitro digestive stability, and anti-Escherichia coli activity.Ultrasonics sonochemistry · 2022Article
- The combination of ultrasound and chlorogenic acid to inactivate Staphylococcus aureus under planktonic, biofilm, and food systems.Ultrasonics sonochemistry · 2021Article
- Novel Hybrid Peptide Cathelicidin 2 (1-13)-Thymopentin (TP5) and Its Derived Peptides with Effective Antibacterial, Antibiofilm, and Anti-Adhesion Activities.International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is drug-resistant and biofilm-forming pathogenic bacteria with severe morbidity and mortality, and has been continuously detected in food products in recent years. Mannosylerythritol lipids (MELs) are novel biosurfactants and perform antibacterial property against gram-positive bacteria. Ultrasound has been applied into food sterilization as non-thermal techniques and has advantage of maintaining food nutrition and flavor over heat pasteurization. In this work, the synergistic treatment of ultrasound and MEL-A was used to combat planktonic cells and biofilm of MRSA. As a result, the combined treatment has exhibited remarkable antibacterial effect proved by enumeration of viable microbes. Furthermore, flow cytometry, scanning electron microscopy and transmission electron microscopy revealed ultrasound has enhanced the inhibitory effect of MEL-A through exacerbating cell membrane damage. On the other hand, the collaborating working modes to eradicate MRSA biofilm were disturbing cell adhesion to surface by MEL-A and destructing mature biofilm mechanically by ultrasound, reaching to over 90% of clearance rate. The findings of this study illustrated the synergistic antimicrobial mechanism of ultrasound and MEL-A treatments, and offered theoretical basis for their potential applications in food preservation.
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