Evidence map›Paper›PMID 33388654›Full record

ArticleBioorganic & medicinal chemistry2021

Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study.

Omar A El-Khouly, Morkos A Henen, Magda A-A El-Sayed, Mona I Shabaan, Shahenda M El-Messery

Open access · greenAbstract read
In one paragraph

Article in Bioorganic & medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Omar A El-KhoulyDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, P.O. Box 35516, Mansoura, Egypt.
Morkos A HenenDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, P.O. Box 35516, Mansoura, Egypt; Department of Biochemistry & Molecular Genetics, University of Colorado, Denver, USA. Electronic address: morkos.henen@ucdenver.edu.
Magda A-A El-SayedDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, P.O. Box 35516, Mansoura, Egypt; Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University, P.O. Box 34518, New Damietta, Egypt.
Mona I ShabaanDepartment of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, P.O. Box 35516, Mansoura, Egypt.
Shahenda M El-MesseryDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, P.O. Box 35516, Mansoura, Egypt. Electronic address: selmessery@gmail.com.
Mansoura University · EG

Funding

600 MHz NMR console and cold probeS10OD025020 · OD · UNIVERSITY OF COLORADO DENVER · PI JONES, DAVID NIGEL · 2018 to 2018
$501k
NIH HHS S10 OD025020
6 · The paper itself

Abstract

A new series of benzofuran derivatives has been designed and synthesized. The structures of the synthesized compounds have been confirmed by the use of

Indexed as

Anti-Bacterial AgentsAntifungal AgentsAntineoplastic AgentsBenzofuransCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorFungiGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsModels, MolecularMolecular StructurePhosphatidylinositol 3-KinasesProtein Kinase InhibitorsAnti-Bacterial AgentsAntifungal AgentsAntineoplastic AgentsbenzofuranBenzofuransPhosphatidylinositol 3-KinasesProtein Kinase InhibitorsAnticancerAntimicrobialBenzofuranHybridizationMolecular modelingNOESYPI3KQuorum sensing

Identifiers

PMID33388654
PMCPMC7902087
OpenAlexW3117689250

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.