Evidence map›Paper›PMID 33388323›Full record

SynthesisPreventive medicine2021

A narrative review of HPV vaccination interventions in rural U.S. communities.

Heather M Brandt, Robin C Vanderpool, Meagan Pilar, Maria Zubizarreta, Lindsay R Stradtman

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
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  6. Identifying HPV vaccination research priorities for the US.Human vaccines & immunotherapeutics · 2025
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  11. What cancers explain the growing rural-urban gap in human papillomavirus-associated cancer incidence?The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Heather M BrandtUniversity of South Carolina Arnold School of Public Health, Department of Health Promotion, Education, Behavior, Rural and Minority Health Research Center, 915 Greene Street, Columbia, SC 29208, United States. Electronic address: hbrandt@sc.edu.
Robin C VanderpoolNational Cancer Institute, Division of Cancer Control and Population Sciences, Health Communication and Informatics Research Branch, 9609 Medical Center Drive, 3E610, Rockville, MD 20850, United States. Electronic address: robin.vanderpool@nih.gov.
Meagan PilarWashington University in St. Louis, Brown School of Social Work, One Brookings Drive, Campus Box 1196, St. Louis, MO 63130, United States. Electronic address: meagan.pilar@wustl.edu.
Maria ZubizarretaUniversity of South Carolina Arnold School of Public Health, Core for Applied Research and Evaluation, 915 Greene Street, Columbia, SC 29208, United States. Electronic address: zubizarr@mailbox.sc.edu.
Lindsay R StradtmanUniversity of Kentucky College of Public Health, Department of Health, Behavior & Society, 113 Washington Avenue, Lexington, KY 40506, United States.
University of South Carolina · USNational Cancer Institute · USUniversity of Kentucky · USWashington University in St. Louis · US

Funding

Rural Cancer Prevention Center __ Early Detection of Colorectal Cancer and PolypsU48DP005014 · DP · UNIVERSITY OF KENTUCKY · PI CROSBY, RICHARD A · 2014 to 2018
$6.3M
Faith, Activity, and Nutrition: Dissemination in Underserved CommunitiesU48DP005000 · DP · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI WILCOX, SARA · 2014 to 2019
$5.9M
NCCDPHP CDC HHS U48 DP005000NCCDPHP CDC HHS U48 DP005014
6 · The paper itself

Abstract

Uptake of human papillomavirus (HPV) vaccine in the United States (U.S.) is far below the Healthy People 2020 goal of 80% coverage among adolescents. In rural communities, HPV vaccination coverage is low, yet incidence and mortality rates of HPV-associated cancer are high. Much of the research focused on HPV vaccination in rural U.S. communities has involved qualitative investigations, observations, survey research, and secondary data analysis with limited implementation of interventional study designs. The purpose of this narrative review was to examine intervention studies to increase HPV vaccination in rural settings and to summarize study characteristics and associated outcomes. PubMed, PsycINFO, CINAHL, and Web of Science were searched utilizing systematic narrative review methodology for studies describing implementation of HPV vaccination interventions in rural U.S. settings from January 2006-December 2019. Using specific search criteria, 991 studies were identified. After abstract review, 30 full-text articles were assessed for eligibility, and 15 met the inclusion criteria. The 15 articles - published from 2011 to 2019 - described HPV vaccination interventions in rural settings of six states, including communities, health clinics, and schools. A range of primary and secondary outcomes were reported, including HPV vaccine receipt (series initiation, continuation, and/or completion); HPV vaccine knowledge; and/or cervical cancer knowledge. Across the studies, there was an absence of the description of rural context. As compared to the broader HPV vaccination intervention literature, interventions in rural settings were limited. More interventional research is needed in rural communities given the elevated rates of HPV-related cancer and low rates of HPV vaccine uptake.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsAdolescentFemaleHumansRural PopulationUnited StatesVaccinationPapillomavirus VaccinesNeoplasmsPapillomavirus vaccinesRural populationsUnited StatesVaccination

Identifiers

PMID33388323
PMCPMC10064483
OpenAlexW3114962909

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.