Evidence map›Paper›PMID 33388247›Full record

ArticleDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver2021

Impact of COVID-19 pandemic on the management of paediatric inflammatory bowel disease: An Italian multicentre study on behalf of the SIGENP IBD Group.

Serena Arrigo, Patrizia Alvisi, Claudia Banzato, Matteo Bramuzzo, Rosaria Celano, Fortunata Civitelli, Giulia D'Arcangelo, Anna Dilillo, Valeria Dipasquale, Enrico Felici and 15 more

Abstract readMulticenter Study
In one paragraph

Article in Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. A Multifaced Aspect ofJournal of personalized medicine · 2023
    Review
  6. Review
  7. Review
  8. Impact of COVID-19 pandemic on pediatric endoscopy: A multicenter study on behalf of the SIGENP Endoscopy Working Group.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2022
    Article
  9. Gastrointestinal, hepatic and pancreatic manifestations of COVID-19 in children.Clinics and research in hepatology and gastroenterology · 2022
    Review
  10. Article
  11. Impact of COVID-19 on Pediatric Immunocompromised Patients.Pediatric clinics of North America · 2021
    Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Serena ArrigoPediatric Gastroenterology and Endoscopy Unit, Institute 'Giannina Gaslini', Genoa, Italy.
Patrizia AlvisiPediatric Gastroenterology Unit, Maggiore Hospital, Bologna, Italy.
Claudia BanzatoDepartment of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona, Italy.
Matteo BramuzzoInstitute for Maternal and Child Health, IRCCS Burlo Garofalo, Trieste, Italy.
Rosaria CelanoFondazione IRCCS Ca' Grande, Ospedale Maggiore Policlinico, Pediatric Intermediate Care Unit, Milan, Italy.
Fortunata CivitelliDepartment of Gender diseases, Child and Adolescent health, Pediatric unit, Sant'Eugenio Hospital, Rome, Italy.
Giulia D'ArcangeloWomen's and Children's Health Department, Pediatric Gastroenterology and Hepatology Unit, Sapienza University of Rome, Rome, Italy.
Anna DililloPediatric and Neonatology Unit, Sapienza University of Rome, Santa Maria Goretti Hospital, Latina, Italy.
Valeria DipasqualePaediatric Gastroenterology and Cystic Fibrosis Unit, Department of Human Pathology in Adult and Developmental Age ``Gaetano Barresi'', University of Messina, Italy.
Enrico FeliciPediatric and Pediatric Emergency Unit, "Umberto Bosio" Center for Digestive Diseases, The Children Hospital, AO SS Antonio e Biagio e C. Arrigo, Alessandria, Italy.
Maurizio FuotiPediatric Gastroenterology and GI Endoscopy, University Department of Pediatrics, Children's Hospital, Spedali Civili, Brescia, Italy.
Simona GattiDepartment of Pediatrics, Università Politecnica delle Marche, Ancona, Italy.
Daniela KnafelzHepatology and Gastroenterology Unit, Bambino Gesù Hospital, Rome, Italy.
Paolo LionettiUniversity of Florence-Meyer Hospital, Florence, Italy.
Federica MarioPediatric Unit, Ca' Foncello's Hospital, Treviso, Italy.
Antonio MarsegliaFondazione IRCCS Casa Sollievo della Sofferenza, Division of Pediatrics, San Giovanni Rotondo, Italy.
Stefano MartelossiPediatric Unit, Ca' Foncello's Hospital, Treviso, Italy.
Chiara MorettiPaediatrics Division, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Lorenzo NorsaPaediatric Hepatology Gastroenterology and Transplantation, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Roberto PanceriDepartment of Pediatrics, University of Milano-Bicocca, Foundation MBBM/San Gerardo Hospital, Monza, Italy.
Sara RenzoUniversity of Florence-Meyer Hospital, Florence, Italy.
Claudio RomanoPaediatric Gastroenterology and Cystic Fibrosis Unit, Department of Human Pathology in Adult and Developmental Age ``Gaetano Barresi'', University of Messina, Italy.
Erminia RomeoDigestive Surgery and Endoscopy Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Caterina StrisciuglioDepartment of Woman, Child and General and Specialistic Surgery, University of Campania ``Luigi Vanvitelli'', Naples, Italy.
Massimo MartinelliDepartment of Translational Medical Science, Section of Pediatrics, University of Naples "Federico II", Italy. Electronic address: massimo.martinelli@unina.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIBD management has been significantly affected during the COVID-19 lockdown with potential clinical issues.

aimsThe aim of this study was to analyse the impact of COVID-19 pandemic on the Italian paediatric IBD cohort.

methodsThis was a multicentre, retrospective, cohort investigation including 21 different Italian IBD referral centres. An electronic data collection was performed among the participating centres including: clinical characteristics of IBD patients, number of COVID-19 cases and clinical outcomes, disease management during the lockdown and the previous 9 weeks.

results2291 children affected by IBD were enrolled. We experienced a significant reduction of the hospital admissions [604/2291 (26.3%) vs 1281/2291 (55.9%); p < 0.001]. More specifically, we observed a reduction of hospitalizations for new diagnosis (from n = 44 to n = 27) and endoscopic re-evaluations (from n = 46 to n = 8). Hospitalization for relapses and surgical procedures remained substantially unchanged. Biologic infusions did not significantly vary [393/2291 (17.1%) vs 368/2291 (16%); p = 0.3]. Telemedicine services for children with IBD were activated in 52.3% of the centres. In 42/2291(1.8%) children immunosuppressive therapies were adapted due to the concurrent COVID-19 pandemic.

conclusionDue to the several limitations of the lockdown, cares for children with IBD have been kept to minimal standards, giving priorities to the urgencies and to biologics' infusions and implementing telemedicine services.

Indexed as

AdolescentBiological ProductsChildColitis, UlcerativeCOVID-19Crohn DiseaseDisease ManagementEndoscopy, GastrointestinalFemaleGastrointestinal AgentsHospitalizationHumansImmunosuppressive AgentsInflammatory Bowel DiseasesItalyMaleBiological ProductsGastrointestinal AgentsImmunosuppressive AgentsCOVID-19immunosuppressionInflammatory Bowel DiseaselockdownPaediatricstelemedicine

Identifiers

PMID33388247
PMCPMC7832380

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.