Evidence map›Paper›PMID 33388071›Full record

ArticleCardiovascular ultrasound2021

Safety and effects of volume loading during transesophageal echocardiography in the pre-procedural work-up for left atrial appendage closure.

Afonso B Freitas-Ferraz, Mathieu Bernier, Kim O'Connor, Jonathan Beaudoin, Jean Champagne, Jean-Michel Paradis, Gilles O'Hara, Guillem Muntané-Carol, Alberto Alperi, Laurent Faroux and 2 more

Abstract read
In one paragraph

Article in Cardiovascular ultrasound, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. A Comprehensive Review of Percutaneous and Surgical Left Atrial Appendage Occlusion.Journal of cardiovascular development and disease · 2024
    Review
  2. Article
  3. Article
  4. Echocardiographic guidance in transcatheter structural cardiac interventions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Afonso B Freitas-FerrazDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Mathieu BernierDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada. Mathieu.bernier@criucpq.ulaval.ca.
Kim O'ConnorDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Jonathan BeaudoinDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Jean ChampagneDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Jean-Michel ParadisDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Gilles O'HaraDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Guillem Muntané-CarolDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Alberto AlperiDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Laurent FarouxDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Lucia JunqueraDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada.
Josep Rodés-CabauDepartment of Cardiology, Quebec Heart & Lung Institute, Laval University, 2725, chemin Sainte-Foy, Quebec City, G1V 4G5, Quebec, Canada. josep.rodes@criucpq.ulaval.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients undergoing left atrial appendage (LAA) closure, an accurate sizing of the LAA is key to optimize device sizing, procedural success and reduce complications. Previous studies have shown that intraprocedural volume loading increases LAA dimensions and improves device sizing. However, the safety and effects on LAA and device sizing of administering a fluid bolus during pre-procedural transesophageal echocardiography (TEE) are unknown. The aim of this study was to determine the safety and impact on LAA dimensions and device sizing of an intravenous (IV) fluid bolus administered during TEE in the setting of the pre-procedural work-up for LAA closure.

methodsThe study included a total of 72 patients who underwent TEE to assess suitability for LAAC and received a 500 ml IV bolus of normal saline. The LAA landing zone (LZ) and depth were measured by TEE before and after volume loading, and these measurements were used to predict the device size implanted during a subsequent percutaneous LAAC procedure.

resultsThere were no complications associated with volume loading. The baseline mean LZ was 19.6 ± 3.6 mm at 90

conclusionsVolume loading during ambulatory TEE as part of the pre-procedural work-up of LAAC is safe and significantly increases LAA dimensions. This strategy may become the new standard, particularly in centers performing LAAC with no TEE guidance, as it improves LAA sizing and more accurately predicts the final device size.

Indexed as

AgedAtrial AppendageAtrial FibrillationCardiac Surgical ProceduresEchocardiography, TransesophagealFemaleHumansMalePreoperative PeriodReproducibility of ResultsRetrospective StudiesAmplatzerLeft atrial appendageLeft atrial appendage closureTransesophageal echocardiographyUltrasealVolume loadingWatchman

Identifiers

PMID33388071
PMCPMC7778814

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.