ArticleBMC cardiovascular disorders2021
Effect of opium consumption on cardiovascular diseases - a cross- sectional study based on data of Rafsanjan cohort study.
Article in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Lipid profile dysregulation in opium users based on Fasa PERSIAN cohort study results.Scientific reports · 2021Trial
- Investigating the role of opium consumption in the severity, and outcome of COVID-19.BMC infectious diseases · 2026Article
- High incidence of post-discharge cardiovascular mortality after COVID-19 hospitalization: a data-linkage study in Southern Iran.BMC cardiovascular disorders · 2026Article
- Astrocytes and Astrocyte-Derived Extracellular Conduits in Opiate-Mediated Neurological Disorders.Cells · 2025Review
- Kidney stone and risk of cardiovascular diseases: a cross-sectional study in the southeast of Iran.BMC nephrology · 2025Article
- Investigating the relationship between opium use and coronary slow flow: a propensity score matched case-control study.BMJ open · 2024Article
- Office-based risk equation of Globorisk for prediction of ten-years cardiovascular risk among Iranian population: findings from Fasa PERSIAN cohort study.BMC medical research methodology · 2024Article
- Metabolic syndrome: a population-based study of prevalence and risk factors.Scientific reports · 2024Article
- Association between DMFT and primary headaches: a study based on the Rafsanjan cohort study.BMC oral health · 2024Article
- Prevalence of major non-communicable diseases and their associated risk factors in Afghanistan: a systematic review and meta-analysis.Therapeutic advances in chronic disease · 2024Review
- Long-Term Effects of Opium Consumption Following Percutaneous Coronary Intervention: A 10-year Follow-Up Study.Global heart · 2024Article
- Opioid Use Disorder and intracerebral hemorrhage in Isfahan, Iran: a case-control study.Frontiers in neurology · 2024Article
- The profile of Oral Health Branch of Rafsanjan Cohort Study (OHBRCS) in Rafsanjan City, southeast of Iran.Preventive medicine reports · 2023Article
- Association between inter-arm blood pressure difference and cardiovascular disease: result from baseline Fasa Adults Cohort Study.Scientific reports · 2023Article
- Association of Opium Consumption and Coronary Artery Ectasia: A Propensity Score-Matched Study.Archives of Iranian medicine · 2022Article
- The prevalence and predictors of cardiovascular diseases in Kherameh cohort study: a population-based study on 10,663 people in southern Iran.BMC cardiovascular disorders · 2022Article
- Examining the association between opium use, cigarette smoking and alcohol consumption with the liver enzyme levels in a population-based study: Fasa Persian cohort data.BMC research notes · 2022Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are differences of opinion about the beneficial or detrimental effects of opium consumption on cardiovascular diseases (CVDs). So, we aimed to study the association between opium use and CVDs.
methodsWe used data obtained from the Rafsanjan Cohort Study (RCS), as a part of the prospective epidemiological research studies in IrAN (PERSIAN), with detailed, validated data on opium consumption and some other exposures. A total of 10,000 adults were enrolled in the study. Logistic regression models were used to assess the possible relationships of opium consumption with the prevalence of ischemic heart diseases (IHD) and myocardial infarction (MI).
resultsIn this study, 9990 participants in the baseline phase of the Rafsanjan adult cohort study were included according to their completed questionnaire. Among all participants, 870 and 296 individuals were found to suffer from IHD and MI, respectively. Opium consumption was found to be relatively high in the RCS participants, especially in men (men = 2150 and women = 228). Opium use was associated with a higher odds of IHD and MI, with the adjusted odds ratios (95% CI) of 1.51 (1.22-1.86) and 1.79 (1.31-2.45), respectively. Also, dose-response increases were observed with the highest odds ratios in the 4th quartile for MI and IHD (p-values for trend < 0.001). Increased odds were observed for the two main methods of opium consumption, i.e. oral and smoking, but oral administration had higher odds ratio.
conclusionsOpium consumption is associated with the increased odds of both IHD and MI diseases.
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