Evidence map›Paper›PMID 33387274›Full record

ArticleBiological trace element research2021

Effects of Selenium on the Immunotoxicity of Subacute Arsenic Poisoning in Chickens.

Zhihua Ren, Qiang Wu, Huidan Deng, Yueru Yu, Wenjiao Tang, Youtian Deng, Ling Zhu, Ya Wang, Junliang Deng

Abstract read
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Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhihua RenCollege of Veterinary Medicine, Sichuan Agricultural University, Ya'an, 625014, China.
Qiang WuLeshan City, Shizhong District of Animal Husbandry Bureau, Leshan, 614000, China.
Huidan DengCollege of Veterinary Medicine, Sichuan Agricultural University, Ya'an, 625014, China.
Yueru YuCollege of Veterinary Medicine, Sichuan Agricultural University, Ya'an, 625014, China.
Wenjiao TangLeshan City, Shizhong District of Animal Husbandry Bureau, Leshan, 614000, China.
Youtian DengCollege of Veterinary Medicine, Sichuan Agricultural University, Ya'an, 625014, China.
Ling ZhuCollege of Veterinary Medicine, Sichuan Agricultural University, Ya'an, 625014, China.
Ya WangCollege of Veterinary Medicine, Sichuan Agricultural University, Ya'an, 625014, China.
Junliang DengCollege of Veterinary Medicine, Sichuan Agricultural University, Ya'an, 625014, China. dengjl213@126.com.
Sichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to determine the effects of selenium on the immune toxicity of subacute arsenic poisoning in chickens. Two hundred 8-day-old broilers were randomly divided into 5 groups: the control group (0.1 mg/kg As + 0.2 mg/kg Se), the As group (3 mg/kg As + 0.2 mg/kg Se), As + Se group I (3 mg/kg As + 5 mg/kg Se), As + Se group II (3 mg/kg As + 10 mg/kg Se), and As + Se group III (3 mg/kg As + 15 mg/kg Se). The conclusions were drawn based on the following measurements: 3.0 mg/kg added to feed led to a decrease in the growth performance of the broilers, reduced the level and conversion rate of ANAE, reduced the blood protein content of the broilers but had no effect on the albumin/globulin ratio, and had an inhibitory effect on erythrocyte immunity. Selenium-added of 5 and 10 mg/kg in daily feed leads to increased growth performance, increases the positive rate and conversion rate of ANAE, increases the hemoglobin content of broilers, and promotes erythrocyte immunity, which indicates that the selenium-added reduces the toxic effects of arsenic; 3.0 mg/kg arsenic with 15 mg/kg selenium had the most severe toxic effects. Fifteen milligrams per kilogram of selenium added in daily feed increases the toxicity of arsenic to broilers. The dose of 10 mg/kg selenium showed the best inhibitory effect on subacute arsenic poisoning in the broilers.

Indexed as

ArsenicArsenic PoisoningSeleniumAnimal FeedAnimalsAntioxidantsChickensDietDietary SupplementsAntioxidantsArsenicSeleniumArsenic toxicityBroilerCell immunityGrowth performanceHumoral immunitySelenium

Identifiers

PMID33387274
OpenAlexW3116974903

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.