ReviewGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2021
Gastric equivalent of the 'Holy Plane' to standardize the surgical concept of stomach cancer to mesogastric excision: updating Jamieson and Dobson's historic schema.
Review in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- Revising Fascial Anatomy With a Focus on the Fusion Fascia in Mesenteric Gastrointestinal Cancer Surgery.Annals of gastroenterological surgery · 2026Review
- Laparoscopic total gastrectomy for advanced gastric cancer with anomalous splenic vein and hepatic artery: a case report.BMC surgery · 2026Article
- The right hemicolon fascial system: a narrative review.Frontiers in surgery · 2026Review
- Reframing gastric lymph nodes as a parapancreatic lymph chain: an embryology-driven rationale for omento-bursectomy and omentum-preserving gastrectomy to facilitate safe infrapyloric lymph node dissection.World journal of surgical oncology · 2025Review
- Author response to: Comment on: "Gastric equivalent of the 'Holy Plane' to standardize the surgical concept of stomach cancer to mesogastric excision: updating Jamieson and Dobson's historic schema".Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025Article
- Comment on:"Gastric equivalent of the 'Holy Plane' to standardize the surgical concept of stomach cancer to mesogastric excision: updating Jamieson and Dobson's historic schema," Gastric cancer, 2021 Jan 2, by Hisashi Shinohara et al.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025Article
- Bi-regional and bi-phasic automated machine learning radiomics for defining metastasis to lesser curvature lymph node stations in gastric cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Article
- AI-based visualization of loose connective tissue as a dissectable layer in gastrointestinal surgery.Scientific reports · 2025Article
- Laparoscopic radical gastrectomy for gastric cancer: an anatomical approach to right mesogastrium excision and its clinical significance.Frontiers in oncology · 2025Article
- Elevated Levels of MUC and JADE1 Predict Poor Prognosis of Patients with Gastric Cancer.Cancer management and research · 2025Article
- The short- and long-term outcomes of laparoscopic D2 lymphadenectomy plus complete mesogastrium excision for lymph node-negative gastric cancer.Surgical endoscopy · 2024Article
- Review
- Surgery utilizing artificial intelligence technology: why we should not rule it out.Surgery today · 2023Review
- Proposal for T3 classification of esophagogastric junction carcinoma based on the interconnection of extramural anatomical structures.Esophagus : official journal of the Japan Esophageal Society · 2023Review
- EIF4A3 induced circABCA5 promotes the gastric cancer progression by SPI1 mediated IL6/JAK2/STAT3 signaling.American journal of cancer research · 2023Article
- Reducing the risk of postoperative pancreatic fistula in radical gastrectomy: pre-assessment with computed tomography for the diagnosis of pancreatic steatosis.Langenbeck's archives of surgery · 2022Article
- Can a single-port robot be safely used for robotic total gastrectomy for advanced gastric cancer? First experience using the da Vinci SP platform.Gastroenterology report · 2022Article
- Automated segmentation by deep learning of loose connective tissue fibers to define safe dissection planes in robot-assisted gastrectomy.Scientific reports · 2021Article
- Extensive Dissection at No. 12 Station During D2 Lymphadenectomy Improves Survival for Advanced Lower-Third Gastric Cancer: A Retrospective Study From a Single Center in Southern China.Frontiers in oncology · 2021Article
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3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSurgery for curable gastric cancer has historically involved dissection of lymph nodes, depending on the risk of metastasis. By establishing the concept of mesogastric excision (MGE), we aim to make this approach compatible with that for colorectal cancer, where the standard is excision of the mesentery.
methodsCurrent advances in molecular embryology, visceral anatomy, and surgical techniques were integrated to update Jamieson and Dobson's schema, a historical reference for the mesogastrium.
resultsThe mesogastrium develops with a three-dimensional movement, involving multiple fusions with surrounding structures (retroperitoneum or other mesenteries) and imbedding parenchymal organs (pancreas, liver, and spleen) that grow within the mesentery. Meanwhile, the fusion fascia and the investing fascia interface with adjacent structures of different embryological origin, which we consider to be equivalent to the 'Holy Plane' in rectal surgery emphasized by Heald in the concept of total mesorectal excision. Dissecting these fasciae allows for oncologic MGE, consisting of removing lymph node-containing mesenteric adipose tissue with an intact fascial package. MGE is theoretically compatible with its colorectal counterpart, although complete removal of the mesogastrium is not possible due to the need to spare imbedded vital organs. The celiac axis is treated as the central artery of the mesogastrium, but is peripherally ligated by tributaries flowing into the stomach to feed the spared organs.
conclusionThe obscure contour of the mesogastrium can be clarified by thinking of it as the gastric equivalent of the 'Holy Plane'. MGE could be a standard concept for surgical treatment of stomach cancer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.