Evidence map›Paper›PMID 33387116›Full record

ArticleBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2021

Levels of major and trace metals in the scalp hair of Crohn's disease patients: correlations among transition metals.

Hideki Ogasawara, Moriaki Hayasaka, Atsuo Maemoto, Shigeru Furukawa, Takahiro Ito, Osamu Kimura, Tetsuya Endo

Abstract read
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In one paragraph

Article in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hideki OgasawaraKashiwaba Neurosurgical Hospital, E1-15-20, Tsukisamu, Toyohira-Ku, Sapporo, Hokkaido, 062-8513, Japan.
Moriaki HayasakaSchool of Pharmaceutical Sciences, Health Sciences University of Hokkaido, 1757, Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan.
Atsuo MaemotoSapporo Higashi Tokushukai Hospital, N33-E14, Higashi-Ku, Sapporo, Hokkaido, 065-0033, Japan.
Shigeru FurukawaSapporo Higashi Tokushukai Hospital, N33-E14, Higashi-Ku, Sapporo, Hokkaido, 065-0033, Japan.
Takahiro ItoSapporo Higashi Tokushukai Hospital, N33-E14, Higashi-Ku, Sapporo, Hokkaido, 065-0033, Japan.
Osamu KimuraSchool of Pharmaceutical Sciences, Health Sciences University of Hokkaido, 1757, Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan.
Tetsuya EndoSchool of Pharmaceutical Sciences, Health Sciences University of Hokkaido, 1757, Kanazawa, Ishikari-Tobetsu, Hokkaido, 061-0293, Japan. endotty531115@gmail.com.
Health Sciences University of Hokkaido · JPSapporo Higashi Tokushukai Hospital · JPSapporo Azabu Neurosurgical Hospital · JP

Funding

Japan Society for promotion of Science 16K00863Japan Society for Promotion of Science 17K00870
6 · The paper itself

Abstract

Concentrations of 16 metals in the scalp hair of male Crohn's disease (CD) patients (n = 28) were compared to those of male control subjects (n = 25). The majority of patients (n = 20) took an anti-inflammatory agent (mesalazine), and several patients underwent colectomy. A low concentration of serum ferritin was observed in approximately 50% of CD patients due to Fe-deficiency anemia. The concentrations of Fe, Cr, and Co in the hair of CD patients were significantly higher than those of control subjects, and particularly high concentrations were found in CD patients with low serum ferritin. Significant correlations were found among the concentrations of Fe, Cr, and Co in the hair of CD patients, but not in control subjects. In agreement with previous reports, a significant negative correlation was found between ferritin and transferrin concentrations in serum, although the available data in this study was limited (n = 8). Transferrin not only binds to Fe

Indexed as

AdolescentAdultCrohn DiseaseHairHumansMaleMetalloidsMiddle AgedScalpTrace ElementsYoung AdultMetalloidsTrace ElementsAnemiaChromiumCobaltManganeseMesalazine (5-aminosalicylic acid)Nickel

Identifiers

PMID33387116
OpenAlexW3114372532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.