Evidence map›Paper›PMID 33386970›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Changes in olfactory function and olfactory bulb after treatment for acromegaly.

Nazan Degirmenci, Hasan Bektas, Erol Senturk, Muzaffer Ilhan, Alev Gunaldi, Esra Ummuhan Mermi Yetis, Sabri Baki Eren

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04138537 (Olfactory Function and Olfactory Bulb Volume in Acromegaly Patients), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04138537 nacompletednot on this map

Olfactory Function and Olfactory Bulb Volume in Acromegaly Patients

TypeinterventionalSponsorBezmialem Vakif UniversityRan2018 to 2020Enrolled40ConditionsAcromegaly, Olfactory DisorderArmsOB volume, CCCRC test
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nazan DegirmenciDepartment of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey. nzndegirmenci@hotmail.com.ORCID http://orcid.org/0000-0003-0769-9734
Hasan BektasDepartment of Otorhinolaryngology and Head and Neck Surgery, Siirt State Hospital, Siirt, Turkey.
Erol SenturkDepartment of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey.
Muzaffer IlhanDepartment of Endocrinology, Bezmialem Vakif University, Istanbul, Turkey.
Alev GunaldiDepartment of Radiology, Maltepe University, Istanbul, Turkey.
Esra Ummuhan Mermi YetisDepartment of Radiology, Maltepe University, Istanbul, Turkey.
Sabri Baki ErenDepartment of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to investigate the olfactory functions of the acromegaly patients and to discuss the possible causes of olfactory dysfunction in acromegaly patients.

methodsA case-control study was carried out in a tertiary referral center. 52 patients with acromegaly (Acromegaly group) and 52 healthy individuals (Control group) were included in the study. All acromegaly patients included in the study were in the late postoperative period. The Connecticut Chemosensory Clinical Research Center (CCCRC) test was carried out and olfactory bulb (OB) volumes were measured in both of the groups.

resultsThere was a significant difference between the mean CCCRC total scores of the acromegaly and control groups (p = .000). The mean of right and left OB volumes in the acromegaly group was significantly higher than the control group (p = .004)

conclusionIn this study, we found that acromegaly patients are likely to experience olfactory dysfunction. It is important to examine these patients' olfactory functions at the time of diagnosis and clinic follow-up. CLINICAL TRIAL NUMBER: NCT04138537.

Indexed as

AcromegalyOlfaction DisordersCase-Control StudiesHumansMagnetic Resonance ImagingOlfactory BulbSmellAcromegalyOlfactionOlfactory bulbOlfactory dysfunction

Identifiers

PMID33386970

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