Evidence map›Paper›PMID 33386467›Full record

ArticleCancer immunology, immunotherapy : CII2021

Immuno-PET imaging of

Qingzhu Liu, Lei Jiang, Ke Li, Hang Li, Gaochao Lv, Jianguo Lin, Ling Qiu

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Automated and manual synthesis of [EJNMMI radiopharmacy and chemistry · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Preclinical evaluation and preliminary clinical study ofCancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  9. Article
  10. Article
  11. PET imaging of PD-L1 with a small molecule radiotracer.European journal of nuclear medicine and molecular imaging · 2024
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Development and Preclinical Evaluation of [Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Qingzhu Liu *NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Lei Jiang *Department of Nuclear Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, China.
Ke LiNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Hang LiNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Gaochao LvNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China.
Jianguo LinNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China. linjianguo@jsinm.org.ORCID http://orcid.org/0000-0003-1018-9794
Ling QiuNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, China. qiuling@jsinm.org.
Key Laboratory of Nuclear Radiation and Nuclear Energy Technology · CNJiangsu Second Normal University · CNJiangsu University · CNTongji University · CN

Funding

Innovation Capacity Development Plan of Jiangsu Province BM2018023Key Youth Medical Talent Project of Jiangsu Province QNRC2016626Key Youth Medical Talent Project of Jiangsu Province QNRC2016629Major Scientific Research Project of Wuxi Commission of Health Z201913National Natural Science Foundation of China 22076069National Natural Science Foundation of China 81971645National Natural Science Foundation of China 81972906Natural Science Foundation of Jiangsu Province BK20181128Natural Science Foundation of Jiangsu Province BK20201135Precision Medical Project of Wuxi Commission of Health and Family Planning J201806
6 · The paper itself

Abstract

The checkpoint blockade immunotherapy has become a potent treatment strategy for cancers, and programmed death ligand-1 (PD-L1) is a prominent checkpoint ligand that is highly expressed in some cancers. The identification of immune checkpoint marker PD-L1 is critical for improving the success of immunotherapy. Accordingly, the binding specificity and dynamic monitoring property of a non-blocking nanobody tracer

Indexed as

AnimalsAntineoplastic AgentsApoptosisB7-H1 AntigenCell ProliferationCisplatinColonic NeoplasmsFemaleGallium RadioisotopesGliomaHumansMiceMice, Inbred BALB CMice, NudePositron-Emission TomographyRadiopharmaceuticalsAntineoplastic AgentsB7-H1 AntigenCD274 protein, humanCisplatinGallium RadioisotopesRadiopharmaceuticalsSingle-Domain Antibodies18F-FDG68GaNanobody tracerPD-L1PET imaging

Identifiers

PMID33386467
PMCPMC10992594
OpenAlexW3114360788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.