ArticleWorld journal of surgery2021
Ideal Surgical Margin to Prevent Early Recurrence After Hepatic Resection for Hepatocellular Carcinoma.
Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Non-Invasive Assessment of Microvascular Invasion Risk in Hepatocellular Carcinoma Using Liquid Biopsy: Translational Insights and Clinical Implications.Diagnostics (Basel, Switzerland) · 2026Review
- Glisson's capsule invasion as a risk factor of multifocal intrahepatic recurrence after hepatectomy for hepatocellular carcinoma: a retrospective single-center cohort study.Updates in surgery · 2025Article
- Review
- MRI-based prediction of the need for wide resection margins in patients with single hepatocellular carcinoma.European radiology · 2025Article
- Impact of inflammation and the immune system on hepatocellular carcinoma recurrence after hepatectomy.Cancer medicine · 2024Review
- Deep learning radiomics based on contrast enhanced MRI for preoperatively predicting early recurrence in hepatocellular carcinoma after curative resection.Frontiers in oncology · 2024Article
- Rational design of NIR-II molecule-engineered nanoplatform for preoperative downstaging and imaging-guided surgery of orthotopic hepatic tumor.Journal of nanobiotechnology · 2023Article
- Gut microbiome as a biomarker for predicting early recurrence of HBV-related hepatocellular carcinoma.Cancer science · 2023Article
- Laparoscopic and open liver resection for hepatocellular carcinoma with type 2 diabetes mellitus: multicenter propensity score-matched study.Hepatology international · 2023Article
- Impact of Surgical Margin Width on Prognosis Following Resection of Hepatocellular Carcinoma Varies on the Basis of Preoperative Alpha-Feto Protein and Tumor Burden Score.Annals of surgical oncology · 2023Article
- Management of early-stage hepatocellular carcinoma: challenges and strategies for optimal outcomes.Journal of liver cancer · 2023Article
- Does Using Indocyanine Green Fluorescence Imaging for Tumors Help in Determining the Safe Surgical Margin in Real-Time Navigation of Laparoscopic Hepatectomy? A Retrospective Study.Annals of surgical oncology · 2023Article
- Perioperative and long-term survival outcomes of laparoscopic versus open hepatectomy for BCLC stage A large hepatocellular carcinoma patients in difficult segments: A two-centre, propensity score matching analysis.Frontiers in oncology · 2023Article
- Resection Margin Width Does Not Influence the Prognosis of Solitary Hepatocellular Carcinoma After Anatomic Resection: A Real-World Study from China.Journal of hepatocellular carcinoma · 2023Article
- Validity of the Algorithm for Liver Resection of Hepatocellular Carcinoma in the Caudate Lobe.World journal of surgery · 2022Article
- Impact of type 2 diabetes mellitus on the prognosis of patients with hepatocellular carcinoma after laparoscopic liver resection: A multicenter retrospective study.Frontiers in oncology · 2022Article
- State-of-the-art surgery for hepatocellular carcinoma.Langenbeck's archives of surgery · 2021Article
- Review
- Revisiting Surgical Strategies for Hepatocellular Carcinoma With Microvascular Invasion.Frontiers in oncology · 2021Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUNDS AND
aimsPostoperative early recurrence after hepatic resection for hepatocellular carcinoma (HCC) poses a challenge to surgeons, and the effect of a surgical margin is still controversial. This study aimed to identify an ideal margin to prevent early recurrence.
methodsA total of 226 consecutive patients who underwent primary curative hepatic resection for solitary and primary HCC were enrolled. The definition of early recurrence was determined using the minimum P value approach. Logistic regression analysis was used to identify the risk factors of early recurrence. The receiver-operating characteristic (ROC) curve was used to identify the optimal cut-off of the surgical margin and early recurrence.
resultsRecurrence within 8 months induced the poorest overall survival (P = 2×10
conclusionsA > 7-mm margin is important to prevent early recurrence. Patients with HCC and alpha-fetoprotein levels > 100 ng/ml, non-capsule formation, or microvascular invasion may have a survival benefit from a ≥ 7-mm margin.
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