Evidence map›Paper›PMID 33386436›Full record

Observational studyEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Tracheostomy in patients with COVID-19: predictors and clinical features.

Jesus Sancho, Santos Ferrer, Carolina Lahosa, Tomas Posadas, Enric Bures, Pilar Bañuls, Lucia Fernandez-Presa, Pablo Royo, Mª Luisa Blasco, Jaime Signes-Costa

Abstract readObservational Study
In one paragraph

Observational study in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Systematic review and meta-analysis of tracheostomy outcomes in COVID-19 patients.The British journal of oral & maxillofacial surgery · 2021
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jesus SanchoRespiratory Medicine Department, Hospital Clínico Universitario, Avd Blasco Ibañez 17, 46010, Valencia, Spain. jesus.sancho@uv.es.ORCID http://orcid.org/0000-0002-5778-5983
Santos FerrerRespiratory Medicine Department, Hospital Clínico Universitario, Avd Blasco Ibañez 17, 46010, Valencia, Spain.
Carolina LahosaRespiratory Medicine Department, Hospital Clínico Universitario, Avd Blasco Ibañez 17, 46010, Valencia, Spain.
Tomas PosadasRespiratory Medicine Department, Hospital Clínico Universitario, Avd Blasco Ibañez 17, 46010, Valencia, Spain.
Enric BuresRespiratory Medicine Department, Hospital Clínico Universitario, Avd Blasco Ibañez 17, 46010, Valencia, Spain.
Pilar BañulsRespiratory Medicine Department, Hospital Clínico Universitario, Avd Blasco Ibañez 17, 46010, Valencia, Spain.
Lucia Fernandez-PresaRespiratory Medicine Department, Hospital Clínico Universitario, Avd Blasco Ibañez 17, 46010, Valencia, Spain.
Pablo RoyoRespiratory Medicine Department, Hospital Clínico Universitario, Avd Blasco Ibañez 17, 46010, Valencia, Spain.
Mª Luisa BlascoInstitue of Health Research INCLIVA, Valencia, Spain.
Jaime Signes-CostaRespiratory Medicine Department, Hospital Clínico Universitario, Avd Blasco Ibañez 17, 46010, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAround 20% of patients hospitalized for COVID-19 need mechanical ventilation (MV). MV may be prolonged, thus warranting tracheostomy.

methodsObservational cohort study enrolling patients admitted due to COVID-19. Demographic and clinical data at hospital and ICU admission were collected. The primary endpoint was to identify parameters associated with a need for tracheostomy; secondary endpoints were to analyze the clinical course of patients who needed tracheostomy.

results118 patients were enrolled; 37 patients (31.5%) were transferred to ICU, of which 11 (29.72%) needed a tracheostomy due to prolonged MV. Sequential Organ Failure Assessment (SOFA) score at ICU admission (OR 0.65, 95% CI 0.47-0.92, p 0.015) was the only variable found to be associated with increased risk of the need for tracheostomy, with a cut-off point of 4.5 (sensitivity 0.72, specificity 0.73, positive predictive value 0.57 and negative predictive value 0.85). The main complications were nosocomial infection (100%), supraventricular cardiac arrhythmia (45.5%), agitation (54.5%), pulmonary thromboembolism (9.1%) and depression (9.1%). All patients presented with hypoalbuminemia and significant critical illness polyneuropathy.

conclusionSOFA at ICU admission is associated with an increased risk of tracheostomy in patients with COVID-19. Moreover, they present clinical features similar to those with chronic critical illness and suffer SARS-CoV-2-related complications.

Indexed as

COVID-19Cross InfectionHumansRespiration, ArtificialSARS-CoV-2TracheostomyCOVID-19Prolonged mechanical ventilationRespiratory failureTracheostomy

Identifiers

PMID33386436
PMCPMC7775730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.