ArticlePlant cell reports2021
Overexpressing a NPR1-like gene from Citrus paradisi enhanced Huanglongbing resistance in C. sinensis.
Article in Plant cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 45 citations in OpenAlex.
- Proteomic analysis may explain differences inPlant signaling & behavior · 2026Article
- Selective Autophagy Receptor CsNBR1 Confers Citrus Huanglongbing Resistance by Degrading 'Candidatus Liberibacter Asiaticus' Virulence Effectors.Molecular plant pathology · 2026Article
- Article
- Expression characteristics ofPlant signaling & behavior · 2025Article
- Molecular Cloning, Bioinformatics, and Expression Analysis of thePlants (Basel, Switzerland) · 2025Article
- Role of biotechnology for shelf-life extension and quality improvement of perishable fruits and vegetables: a comprehensive review.Food science and biotechnology · 2025Review
- NPR1 suppresses Candidatus Liberibacter asiaticus-induced callose and reactive oxygen species accumulation.Plant physiology · 2025Article
- "Candidatus Liberibacter asiaticus" Infection Induces Citric Acid Accumulation and Immune Responses Mediated by the Transcription Factor CitPH4.Molecular plant pathology · 2025Article
- Genome editing of NPR3 confers potato resistance to Candidatus Liberibacter spp.Plant biotechnology journal · 2024Article
- Transcriptome analysis of Citrus sinensis reveals potential responsive events triggered by Candidatus Liberibacter asiaticus.Protoplasma · 2024Article
- Homobrassinolide Delays Huanglongbing Progression in Newly Planted Citrus (Plants (Basel, Switzerland) · 2024Article
- NPR1, a key immune regulator for plant survival under biotic and abiotic stresses.Molecular cell · 2024Review
- Genome-wide analysis ofFrontiers in plant science · 2024Article
- Investigation of the anti-Huanglongbing effects using antimicrobial lipopeptide and phytohormone complex powder prepared fromFrontiers in microbiology · 2024Article
- Swords and shields: the war betweenFrontiers in plant science · 2024Review
- Overexpressing CsSABP2 enhances tolerance to Huanglongbing and citrus canker inFrontiers in plant science · 2024Article
- Plant volatile-triggered defense in citrus against biotic stressors.Frontiers in plant science · 2024Article
- Variation in microbial feature perception in the Rutaceae family with immune receptor conservation in citrus.Plant physiology · 2023Article
- A Sec-dependent effector, CLIBASIA_04425, contributes to virulence in 'Frontiers in plant science · 2023Article
- A chromosome-level phased genome enabling allele-level studies in sweet orange: a case study on citrus Huanglongbing tolerance.Horticulture research · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
key messageOverexpression of CiNPR4 enhanced resistance of transgenic citrus plants to Huanglongbing by perceiving the salicylic acid and jasmonic acid signals and up-regulating the transcriptional activities of plant-pathogen interaction genes. Developing transgenic citrus plants with enhanced immunity is an efficient strategy to control citrus Huanglongbing (HLB). Here, a nonexpressor of pathogenesis-related gene 1 (NPR1) like gene from HLB-tolerant 'Jackson' grapefruit (Citrus paradisi Macf.), CiNPR4, was introduced into 'Wanjincheng' orange (Citrus sinensis Obseck). CiNPR4 expression was determined in transgenic citrus plants using quantitative real-time PCR analyses. The Candidatus Liberibacter asiaticus (CLas) pathogen of HLB was successfully transmitted to transgenic citrus plants by grafting infected buds. HLB symptoms developed in transgenic and wild-type (WT) plants by 9 months after inoculation. A CLas population analysis showed that 26.9% of transgenic lines exhibited significantly lower CLas titer levels compared with the CLas-infected WT plants at 21 months after inoculation. Lower starch contents and anatomical aberration levels in the phloem were observed in transgenic lines having enhanced resistance compared with CLas-infected WT plants. CiNPR4 overexpression changed the jasmonic acid, but not salicylic acid, level. Additionally, the jasmonic acid and salicylic acid levels increased after CLas infection. Transcriptome analyses revealed that the enhanced resistance of transgenic plants to HLB resulted from the up-regulated transcriptional activities of plant-pathogen interaction-related genes.
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