ArticleLight, science & applications2021
Adaptive dynamic range shift (ADRIFT) quantitative phase imaging.
Article in Light, science & applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 313 citations in OpenAlex.
- Background-free quantitative phase imaging with adaptive-optics surface plasmon resonance holographic microscopy.Light, science & applications · 2026Article
- Bidirectional quantitative scattering microscopy.Nature communications · 2025Article
- Advanced vibrational microscopes for life science.Nature methods · 2025Review
- Imaging cells and nanoparticles using modulated optically computed phase microscopy.Scientific reports · 2025Article
- A tutorial on optical photothermal infrared (O-PTIR) microscopy.APL photonics · 2024Article
- Phase-shifting optothermal microscopy enables live-cell mid-infrared hyperspectral imaging of large cell populations at high confluency.Science advances · 2024Article
- Time-Resolved Mid-Infrared Photothermal Microscopy for Imaging Water-Embedded Axon Bundles.Analytical chemistry · 2023Article
- Label-free mid-infrared photothermal live-cell imaging beyond video rate.Light, science & applications · 2023Article
- Video-rate mid-infrared photothermal imaging by single-pulse photothermal detection per pixel.Science advances · 2023Article
- Bond-selective intensity diffraction tomography.Nature communications · 2022Article
- Background-Suppressed High-Throughput Mid-Infrared Photothermal Microscopy via Pupil Engineering.ACS photonics · 2021Article
- Bond-selective imaging by optically sensing the mid-infrared photothermal effect.Science advances · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Quantitative phase imaging (QPI) with its high-contrast images of optical phase delay (OPD) maps is often used for label-free single-cell analysis. Contrary to other imaging methods, sensitivity improvement has not been intensively explored because conventional QPI is sensitive enough to observe the surface roughness of a substrate that restricts the minimum measurable OPD. However, emerging QPI techniques that utilize, for example, differential image analysis of consecutive temporal frames, such as mid-infrared photothermal QPI, mitigate the minimum OPD limit by decoupling the static OPD contribution and allow measurement of much smaller OPDs. Here, we propose and demonstrate supersensitive QPI with an expanded dynamic range. It is enabled by adaptive dynamic range shift through a combination of wavefront shaping and dark-field QPI techniques. As a proof-of-concept demonstration, we show dynamic range expansion (sensitivity improvement) of QPI by a factor of 6.6 and its utility in improving the sensitivity of mid-infrared photothermal QPI. This technique can also be applied for wide-field scattering imaging of dynamically changing nanoscale objects inside and outside a biological cell without losing global cellular morphological image information.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.