Evidence map›Paper›PMID 33386320›Full record

ArticlePediatrics2021

Principles of Care for Young Adults With Co-Occurring Psychiatric and Substance Use Disorders.

Andrea E Spencer, Sarah E Valentine, Jennifer Sikov, Amy M Yule, Heather Hsu, Eliza Hallett, Ziming Xuan, Michael Silverstein, Lisa Fortuna

Abstract read
In one paragraph

Article in Pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  7. Review
  8. Article
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  12. Article
  13. Adolescents' Adverse Childhood Experiences, Poor Mental Health, and Substance Use During the COVID-19 Pandemic.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  14. Pathways to recovery model of youth substance misuse in Assam, India.Health expectations : an international journal of public participation in health care and health policy · 2023
    Article
  15. Review
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrea E SpencerDepartments of Psychiatry and andrea.spencer@bmc.org.
Sarah E ValentineDepartments of Psychiatry and.
Jennifer SikovDepartments of Psychiatry and.
Amy M YuleDepartments of Psychiatry and.
Heather HsuBoston Medical Center, Boston, Massachusetts; and.
Eliza HallettBoston Medical Center, Boston, Massachusetts; and.
Ziming XuanSchool of Public Health, Boston University, Boston, Massachusetts.
Michael SilversteinBoston Medical Center, Boston, Massachusetts; and.
Lisa FortunaDepartment of Psychiatry, University of California San Francisco, San Francisco, California.

Funding

AACAP Physician Scientist Program in Substance UseK12DA000357 · NIDA · AMERICAN ACADEMY-CHILD/ADOLESCENT PSYCH · PI Kevin M. Gray · 1998 to 2026
$29.1M
An implementation science approach to optimizing evidence-based treatments for posttraumatic stress disorder (PTSD) for non-specialty settingsK23MH117221 · NIMH · BOSTON MEDICAL CENTER · PI VALENTINE, SARAH E · 2018 to 2022
$908k
Developing a Pediatrics-based Social Needs Intervention to Reduce Disparities in ADHD Outcomes for Low-income ChildrenK23MH118478 · NIMH · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI SPENCER, ANDREA · 2018 to 2022
$696k
NIDA NIH HHS K12 DA000357NIMH NIH HHS K23 MH117221NIMH NIH HHS K23 MH118478
6 · The paper itself

Abstract

Over 50% of young adults (defined as individuals aged 18-25 years) with substance use disorders (SUDs) have at least 1 co-occurring psychiatric disorder, and the presence of co-occurring disorders worsens SUD outcomes. Treatment of both co-occurring psychiatric disorders and SUDs in young adults is imperative for optimal treatment, yet many barriers exist to achieving this goal. We present a series of evidence-informed principles of care for young adults with co-occurring psychiatric disorders derived by a workgroup of experts convened by Boston Medical Center's Grayken Center for Addiction. The 3 principles are as follows: (1) young adults should receive integrated mental health and addiction care across treatment settings; (2) care should be responsive to the needs of young adults exposed to trauma and other adverse childhood experiences; and (3) treatment programs should regularly assess and respond to the evolving mental health needs, motivations, and treatment goals of young adults with co-occurring disorders. Our guidance for each principle is followed by a review of the evidence supporting that principle, as well as practice considerations for implementation. More research among young adults is critical to identify effective treatments and service systems for those with co-occurring disorders.

Indexed as

Adverse Childhood ExperiencesDelivery of Health Care, IntegratedProgram EvaluationConsensus Statements as TopicDiagnosis, Dual (Psychiatry)HumansMental DisordersSubstance-Related DisordersYoung Adult

Identifiers

PMID33386320
PMCPMC8276159

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.