ReviewTrends in immunology2021
Early Events Triggering the Initiation of a Type 2 Immune Response.
Review in Trends in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Indications for Biological Treatment Combined with Allergen-Specific Immunotherapy: Who Is It Really Intended for?Journal of clinical medicine · 2026Review
- Cancer in disguise: a parasite within.The EMBO journal · 2026Review
- Article
- Transcriptional Profiling of Abomasal Mucosa from Young Calves Experimentally Infected withInternational journal of molecular sciences · 2025Article
- Tissue-Resident Th2 Cells in Type 2 Immunity and Allergic Diseases.Immunological reviews · 2025Review
- Genetics of helminth infections: Immune system response, insights into host-parasite interaction, and drug resistance.Journal of advanced veterinary and animal research · 2025Article
- Editorial overview: Framing the logic of type 2 immunity.Current opinion in immunology · 2025Article
- Article
- Critical and diverse role of alarmin cytokines in parasitic infections.Frontiers in cellular and infection microbiology · 2024Review
- Alcohol-induced liver injury in signalling pathways and curcumin's therapeutic potential.Toxicology reports · 2023Review
- Targeting helminths: The expanding world of type 2 immune effector mechanisms.The Journal of experimental medicine · 2023Review
- Functional Recognition Theory and Type 2 Immunity: Insights and Uncertainties.ImmunoHorizons · 2022Review
- Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering ACell reports · 2022Article
- Host type 2 immune response to xenogeneic serum components impairs biomaterial-directed osteo-regenerative therapies.Biomaterials · 2022Article
- The innate immune system in human kidney inflammaging.Journal of nephrology · 2022Review
- B cell fate mapping reveals their contribution to the memory immune response against helminths.Frontiers in immunology · 2022Article
- Biologics as novel therapeutics for the treatment of allergy: Challenges and opportunities.Frontiers in allergy · 2022Review
- The Influence of Genetic and Environmental Factors and Their Interactions on Immune Response to Helminth Infections.Frontiers in immunology · 2022Review
- Editorial: Activation of Innate Immunity by Allergens and Allergenic Sources.Frontiers in allergy · 2021Article
- Inhalant Mammal-Derived Lipocalin Allergens and the Innate Immunity.Frontiers in allergy · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Type 2 immune responses are typically associated with protection against helminth infections and also with harmful inflammation in response to allergens. Recent advances have revealed that type 2 immunity also contributes to sterile inflammation, cancer, and microbial infections. However, the early events that initiate type 2 immune responses remain poorly defined. New insights reveal major contributions from danger-associated molecular patterns (DAMPs) in the initiation of type 2 immune responses. In this review, we examine the molecules released by the host and pathogens and the role they play in mediating the initiation of mammalian innate type 2 immune responses under a variety of conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.