Evidence map›Paper›PMID 33385757›Full record

Trial reportAddictive behaviors2021

Examining the effects of problematic alcohol use on cigarette abstinence in recently diagnosed cancer patients enrolled in a cessation trial: A secondary analysis.

Joanna M Streck, Kelly A Hyland, Susan Regan, Alona Muzikansky, Nancy A Rigotti, Colin J Ponzani, Giselle K Perez, Sara Kalkhoran, Jamie S Ostroff, Elyse R Park

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Addictive behaviors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Joanna M StreckDepartment of Psychiatry, Massachusetts General Hospital (MGH), Boston, MA, United States; Harvard Medical School, Boston, MA, United States; Tobacco Research and Treatment Center, Department of Medicine and Health Policy Research Center, The Mongan Institute, MGH, Boston, MA, United States. Electronic address: jstreck@mgh.harvard.edu.
Kelly A HylandDepartment of Psychology, University of Southern Florida, Tampa, FL, United States.
Susan ReganHarvard Medical School, Boston, MA, United States; Tobacco Research and Treatment Center, Department of Medicine and Health Policy Research Center, The Mongan Institute, MGH, Boston, MA, United States.
Alona MuzikanskyMGH Center for Biostatistics, Boston, MA, United States.
Nancy A RigottiHarvard Medical School, Boston, MA, United States; Tobacco Research and Treatment Center, Department of Medicine and Health Policy Research Center, The Mongan Institute, MGH, Boston, MA, United States.
Colin J PonzaniTobacco Research and Treatment Center, Department of Medicine and Health Policy Research Center, The Mongan Institute, MGH, Boston, MA, United States.
Giselle K PerezDepartment of Psychiatry, Massachusetts General Hospital (MGH), Boston, MA, United States; Harvard Medical School, Boston, MA, United States; Tobacco Research and Treatment Center, Department of Medicine and Health Policy Research Center, The Mongan Institute, MGH, Boston, MA, United States.
Sara KalkhoranHarvard Medical School, Boston, MA, United States; Tobacco Research and Treatment Center, Department of Medicine and Health Policy Research Center, The Mongan Institute, MGH, Boston, MA, United States.
Jamie S OstroffDepartment of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Elyse R ParkDepartment of Psychiatry, Massachusetts General Hospital (MGH), Boston, MA, United States; Harvard Medical School, Boston, MA, United States; Tobacco Research and Treatment Center, Department of Medicine and Health Policy Research Center, The Mongan Institute, MGH, Boston, MA, United States.
Harvard University · USMemorial Sloan Kettering Cancer Center · USUniversity of South Florida · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Career Development Program in Substance Use and Addiction MedicineK12DA043490 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI A EDEN EVINS, NANCY A RIGOTTI · 2017 to 2026
$4.7M
Integrating Tobacco Treatment into Cancer CareR01CA166147 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PARK, ELYSE R. · 2012 to 2016
$3.6M
Examining Delivery of Integrated Tobacco Treatment in Cancer CareK24CA197382 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PARK, ELYSE R. · 2015 to 2019
$841k
NCI NIH HHS K24 CA197382NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA166147NIDA NIH HHS K12 DA043490
6 · The paper itself

Abstract

aimsAmong people with cancer, dual alcohol and tobacco use increases risk for morbidity and mortality. Most smoking cessation clinical trials with this patient population have excluded individuals with problematic alcohol use. This investigation examined whether problematic alcohol use affects smoking cessation in cancer patients.

methodsMixed-methods secondary analysis of data from the Smokefree Support Study, a randomized-controlled trial examining the efficacy of Intensive (IT; n = 153) vs. Standard Treatment (ST; n = 150) for smoking cessation in newly diagnosed cancer patients. Problematic alcohol use was assessed at enrollment using the Cut-Down-Annoyed-Guilty-Eye-Opener (CAGE), weekly frequency of alcohol use and binge drinking measures. Alcohol use was categorized as: no current alcohol use, moderate and problematic use. The primary outcome was biochemically-confirmed cigarette abstinence at 6-months. A subset of patients (n = 72) completed qualitative exit-interviews.

resultsAmong all participants, biochemically-confirmed cigarette abstinence rates were 25% (n = 32), 28% (n = 27), and 36% (n = 20) for participants reporting no current alcohol use, moderate use, and problematic use, respectively (p = 0.33). In logistic regression analysis, neither problematic alcohol use (AOR = 0.96, 95% CI = 0.35-2.67, p = .94) nor the problematic use by study arm interaction (AOR = 2.22, 95% CI = 0.59-8.39, p = .24) were associated with biochemically-confirmed 6-month abstinence. Qualitatively, participants reported that drinking alcohol triggers urges to smoke.

conclusionNewly diagnosed cancer patients reporting problematic alcohol use were not less likely to quit smoking than those without. Additional research is needed to investigate whether problematic alcohol users may benefit from smoking and alcohol behavior change interventions at the time of cancer diagnosis.

Indexed as

NeoplasmsSmoking CessationTobacco ProductsHumansSmokingTobacco Use Cessation DevicesAlcohol useBinge drinkingCancerCancer patientsCigarette smokingProblematic alcohol useSmoking cessation

Identifiers

PMID33385757
PMCPMC8118391
OpenAlexW3116950492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.