Evidence map›Paper›PMID 33385509›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2021

Genetic Studies of Mental Illness: Are Children Being Left Behind?

Jonathan Posner, Dominik Biezonski, Sarah Pieper, Cristiane S Duarte

Abstract readEditorial
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonathan PosnerColumbia University Vagelos College of Physicians and Surgeons, New York; New York State Psychiatric Institute, New York; Center for Intergenerational Psychiatry at the New York State Psychiatric Institute. Electronic address: jonathan.posner@nyspi.columbia.edu.
Dominik BiezonskiNew York Genome Center, New York.
Sarah PieperColumbia University Vagelos College of Physicians and Surgeons, New York; New York State Psychiatric Institute, New York.
Cristiane S DuarteColumbia University Vagelos College of Physicians and Surgeons, New York; New York State Psychiatric Institute, New York; Center for Intergenerational Psychiatry at the New York State Psychiatric Institute.

Funding

BREAKING THE CYCLE OF INTERGENERATIONAL DISADVANTAGE: NEURODEVELOPMENT AMONG PUERTO RICAN CHILDREN.UH3OD023328 · OD · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI CANINO, GLORISA J, DUARTE, CRISTIANE S. · 2018 to 2022
$18.3M
Three Generations at High and Low Risk for Depression Followed LongitudinallyR01MH036197 · NIMH · YALE UNIVERSITY · PI POSNER, JONATHAN E, WEISSMAN, MYRNA M · 1985 to 2020
$15.0M
Effects of prenatal maternal depression and antidepressant exposures on offspring neurodevelopmental trajectories: A birth cohort studyR01MH119510 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI POSNER, JONATHAN E, TAKSER, LARISSA · 2019 to 2023
$3.2M
Maternal adversity, inflammation, and neurodevelopment: How intergenerational processes perpetuate disadvantage in a low-resource settingR01MH121070 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Cristiane S. Duarte, Andrea Parolin Jackowski · 2020 to 2026
$2.8M
NIH HHS UH3 OD023328NIMH NIH HHS R01 MH036197NIMH NIH HHS R01 MH119510NIMH NIH HHS R01 MH121070
6 · The paper itself

Abstract

Understanding the genetic architecture of psychiatric disorders is paramount to linking psychopathologies to their genetic underpinnings. In turn, this knowledge can inform strategies for identifying high-risk individuals, early intervention, and development of personalized treatment approaches.

Indexed as

Genome-Wide Association StudyMental DisordersChildGenetic Predisposition to DiseaseHumansMultifactorial InheritancePolymorphism, Single Nucleotide

Identifiers

PMID33385509
PMCPMC8184577

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.