Evidence map›Paper›PMID 33385108›Full record

ArticleACS applied nano materials2020

Comprehensive Characterization of Nanosized Extracellular Vesicles from Central and Peripheral Organs : Implications for Preclinical and Clinical Applications.

Subhash Chand, Ala Jo, Neetha Nanoth Vellichirammal, Austin Gowen, Chittibabu Guda, Victoria Schaal, Katherine Odegaard, Hakho Lee, Gurudutt Pendyala, Sowmya V Yelamanchili

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied nano materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Subhash ChandDepartment of Anesthesiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Ala JoCenter for Systems Biology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Neetha Nanoth VellichirammalDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Austin GowenDepartment of Anesthesiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Chittibabu GudaDepartment of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Victoria SchaalDepartment of Anesthesiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Katherine OdegaardDepartment of Anesthesiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Hakho LeeCenter for Systems Biology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Gurudutt PendyalaDepartment of Anesthesiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Sowmya V YelamanchiliDepartment of Anesthesiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PAUL L SORGEN · 2012 to 2026
$59.2M
Therapeutics Core (Page 286)P30MH062261 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BUCH, SHILPA J., FOX, HOWARD S · 2000 to 2021
$37.7M
Nebraska Center for Nanomedicine- Pilot ProjectsP30GM127200 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI OUPICKY, DAVID · 2018 to 2022
$5.7M
Extracellular vesicles, meth relapse and sex differencesR01DA046852 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BEVINS, RICK A, PENDYALA, GURUDUTT · 2018 to 2022
$2.4M
Role of extracellular vesicles in methamphetamine mediated neurotoxicityR01DA042379 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI YELAMANCHILI, SOWMYA · 2016 to 2020
$1.9M
Neuroimmunology of Disease Training ProgramT32NS105594 · NINDS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Aditya N Bade, Howard E Gendelman · 2018 to 2026
$1.4M
High-throughput Integrated Magneto-electrochemical Exosome (HiMEX) platform to identify neurodevelopmental markers associated with pre and postnatal oxycodone exposureR21DA049577 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO, PENDYALA, GURUDUTT · 2019 to 2020
$458k
Role of extracellular vesicles in methamphetamine and HIV induced neurotoxicityR21DA046855 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KASHANCHI, FATAH, YELAMANCHILI, SOWMYA · 2018 to 2019
$436k
NIDA NIH HHS R01 DA042379NIDA NIH HHS R01 DA046852NIDA NIH HHS R21 DA046855NIDA NIH HHS R21 DA049577NIGMS NIH HHS P20 GM103427NIGMS NIH HHS P30 GM127200NIMH NIH HHS P30 MH062261NINDS NIH HHS T32 NS105594
6 · The paper itself

Abstract

Extracellular vesicles (EV) are nano-sized vesicles that have been garnering a lot of attention for their valuable role as potential diagnostic markers and therapeutic vehicles for a plethora of pathologies. Whilst EV markers from biofluids such as plasma, serum, urine, cerebrospinal fluid and

Indexed as

Extracellular VesiclesnanoplasmonicNanovesiclesOrgan derived extracellular vesiclesOrgan specific markersQuantitative proteomicsSingle EV imaging

Identifiers

PMID33385108
PMCPMC7771629

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.