Evidence map›Paper›PMID 33384988›Full record

ReviewFrontiers in bioengineering and biotechnology2020

Insight Into Nanoliposomes as Smart Nanocarriers for Greening the Twenty-First Century Biomedical Settings.

K M Aguilar-Pérez, J I Avilés-Castrillo, Dora I Medina, Roberto Parra-Saldivar, Hafiz M N Iqbal

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed.

  1. Article
  2. Article
  3. Utilizing nanotechnology to diagnose and treat central nervous system disorders.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. In vitro activity of nanoliposomal amphotericin B against terbinafine-resistant Trichophyton indotineae isolates.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Unlocking the Potential ofPharmaceutics · 2025
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. NovelHeliyon · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

K M Aguilar-PérezTecnologico de Monterrey, School of Engineering and Sciences, Monterrey, Mexico.
J I Avilés-CastrilloTecnologico de Monterrey, School of Engineering and Sciences, Monterrey, Mexico.
Dora I MedinaTecnologico de Monterrey, School of Engineering and Sciences, Monterrey, Mexico.
Roberto Parra-SaldivarTecnologico de Monterrey, School of Engineering and Sciences, Monterrey, Mexico.
Hafiz M N IqbalTecnologico de Monterrey, School of Engineering and Sciences, Monterrey, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The necessity to develop more efficient, biocompatible, patient compliance, and safer treatments in biomedical settings is receiving special attention using nanotechnology as a potential platform to design new drug delivery systems (DDS). Despite the broad range of nanocarrier systems in drug delivery, lack of biocompatibility, poor penetration, low entrapment efficiency, and toxicity are significant challenges that remain to address. Such practices are even more demanding when bioactive agents are intended to be loaded on a nanocarrier system, especially for topical treatment purposes. For the aforesaid reasons, the search for more efficient nano-vesicular systems, such as nanoliposomes, with a high biocompatibility index and controlled releases has increased considerably in the past few decades. Owing to the stratum corneum layer barrier of the skin, the in-practice conventional/conformist drug delivery methods are inefficient, and the effect of the administered therapeutic cues is limited. The current advancement at the nanoscale has transformed the drug delivery sector. Nanoliposomes, as robust nanocarriers, are becoming popular for biomedical applications because of safety, patient compliance, and quick action. Herein, we reviewed state-of-the-art nanoliposomes as a smart and sophisticated drug delivery approach. Following a brief introduction, the drug delivery mechanism of nanoliposomes is discussed with suitable examples for the treatment of numerous diseases with a brief emphasis on fungal infections. The latter half of the work is focused on the applied perspective and clinical translation of nanoliposomes. Furthermore, a detailed overview of clinical applications and future perspectives has been included in this review.

Indexed as

antifungalbiomedical applicationsdrug-loaded constructsfabrication strategiesinfluencing factorsnanocarriersnanoliposomestargeted drug delivery

Identifiers

PMID33384988
PMCPMC7770187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.