Evidence map›Paper›PMID 33384971›Full record

ReviewFrontiers in cellular and infection microbiology2020

NOX-Dependent Signaling Dysregulation in Severe COVID-19: Clues to Effective Treatments.

Simona Damiano, Concetta Sozio, Giuliana La Rosa, Mariarosaria Santillo

Full text readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. COVID-19, the disease that changed the world.Medicine and pharmacy reports · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Cross-Talk of NADPH Oxidases and Inflammation in Obesity.Antioxidants (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Metal-based complexes against SARS-CoV-2.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Review
  15. Development of Metal Complexes for Treatment of Coronaviruses.International journal of molecular sciences · 2022
    Article
  16. Review
  17. Review
  18. Review
  19. A Bioluminescent 3CLViruses · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simona DamianoDipartimento di Medicina Clinica e Chirurgia, Università di Napoli "Federico II", Napoli, Italy.
Concetta SozioDipartimento di Medicina Clinica e Chirurgia, Università di Napoli "Federico II", Napoli, Italy.
Giuliana La RosaDipartimento di Medicina Clinica e Chirurgia, Università di Napoli "Federico II", Napoli, Italy.
Mariarosaria SantilloDipartimento di Medicina Clinica e Chirurgia, Università di Napoli "Federico II", Napoli, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Oxidative StressSARS-CoV-2Angiotensin-Converting Enzyme 2Cardiovascular DiseasesComorbidityCOVID-19COVID-19 Drug TreatmentDiabetes Mellitus, Type 2Enzyme ActivationEnzyme InhibitorsHumansMetforminNADPH Oxidase 2NADPH OxidasesObesityOxidation-ReductionACE2 protein, humanAngiotensin-Converting Enzyme 2CYBB protein, humanEnzyme InhibitorsMetforminNADPH Oxidase 2NADPH OxidasesProto-Oncogene MasProto-Oncogene ProteinsReactive Oxygen SpeciesReceptors, G-Protein-CoupledReceptors, Virusangiotensin converting enzyme 2cardiovascular diseasescoronavirus disease 2019diabeteshypertensionNOX enzymesobesitysevere acute respiratory syndrome coronavirus 2

Identifiers

PMID33384971
PMCPMC7769936

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.