ArticleJournal of dental sciences2021
Can gingival crevicular blood effectively screen for diabetes in Chinese patients with moderate to severe periodontitis? A pilot study.
Article in Journal of dental sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The reliability of using gingival crevicular blood to measure blood glucose and hba1c levels in the dental setting: a systematic review and meta-analysis.Clinical oral investigations · 2024Pooled it
- Effectiveness of multi-stage diabetes screening in the dental care setting: a scoping literature review.BMC oral health · 2026Article
- Article
- Effect of inflammation on bones in diabetic patients with periodontitis via RANKL/OPG system-A review.Journal of diabetes and metabolic disorders · 2022Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background/purposeThe early diagnosis of diabetes is essential for the prevention of complications. Periodontitis has been identified as the sixth complication of diabetes and chair-side screening may improve diagnosis of diabetes. This study evaluated whether gingival crevicular blood (GCB) available during routine periodontal examination can be used to screen for diabetes in Chinese patients with moderate to severe periodontitis. MATERIALS AND
methodsFinger-stick blood (FSB) and GCB were collected from patients (18 with diabetes and 42 without diabetes) during routine periodontal probing and analyzed for glucose and hemoglobin A1c (HbA1c) levels.
resultsIn the diabetic group, the mean glucose levels in GCB and FSB were 12.21 ± 3.86 and 12.61 ± 4.19 mmol/L respectively, while those of the non-diabetic group were 6.14 ± 0.85 and 6.15 ± 0.87 mmol/L, respectively. The average HbA1c values of the diabetic group were 7.72% ± 1.71% and 7.89% ± 1.78% in GCB and FSB, respectively, while those of the non-diabetic group were 5.28% ± 0.31% and 5.23% ± 0.32%, respectively. Highly significant correlations were found between GCB and FSB glucose levels (r = 0.993 for the diabetic group, and r = 0.977 for the non-diabetic group) and between GCB and FSB HbA1c levels (r = 0.977 for the diabetic group, and r = 0.829 for the non-diabetic group).
conclusionOur study results indicate that GCB available during routine periodontal examination may be acceptable for the analyses of blood glucose and HbA1c levels. The approach is suitable for screening undiagnosed diabetes in a dental setting.
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