ArticleFrontiers in physiology2020
Heart Rate Dependency and Inter-Lead Variability of the T Peak - T End Intervals.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Effects of Prediabetes on Ventricular Repolarization Markers in Electrocardiography.Reviews in cardiovascular medicine · 2025Article
- The Effect of Obesity on Repolarization and Other ECG Parameters.Journal of clinical medicine · 2024Article
- Tpeak-Tend ECG Marker in Obesity and Cardiovascular Diseases: A Comprehensive Review.Scientifica · 2024Review
- Intra-subject stability of different expressions of spatial QRS-T angle and their relationship to heart rate.Frontiers in physiology · 2022Article
- Demographic and Methodological Heterogeneity in Electrocardiogram Signals From Guinea Pigs.Frontiers in physiology · 2022Article
- Examination of New Electrocardiographic Repolarization Markers in Diabetic Patients with Noncritical Coronary Artery Disease.International journal of clinical practice · 2022Article
- Sex and Rate Change Differences in QT/RR Hysteresis in Healthy Subjects.Frontiers in physiology · 2021Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
Abstract
The electrocardiographic (ECG) assessment of the T peak-T end (Tpe) intervals has been used in many clinical studies, but several related physiological aspects have not been reported. Specifically, the sources of the Tpe differences between different ECG leads have not been systematically researched, the relationship of Tpe duration to underlying heart rate has not been firmly established, and little is known about the mutual correspondence of Tpe intervals measured in different ECG leads. This study evaluated 796,620 10-s 12-lead ECGs obtained from long-term Holters recorded in 639 healthy subjects (311 female) aged 33.8 ± 9.4 years. For each ECG, transformation to orthogonal XYZ lead was used to measure Tpe in the orthogonal vector magnitude (used as a reference for lead-to-lead comparisons) and to construct a three-dimensional T wave loop. The loop roundness was expressed by a ratio between its circumference and length. These ratios were significantly related to the standard deviation of Tpe durations in different ECG leads. At the underlying heart rate of 60 beats per minute, Tpe intervals were shorter in female than in male individuals (82.5 ± 5.6 vs 90.0 ± 6.5 ms,
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Registered trials
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