Evidence map›Paper›PMID 33384591›Full record

ArticleFrontiers in behavioral neuroscience2020

Cannabidiol Acts at 5-HT

Christopher Martínez-Aguirre, Francia Carmona-Cruz, Ana Luisa Velasco, Francisco Velasco, Gustavo Aguado-Carrillo, Manola Cuéllar-Herrera, Luisa Rocha

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Cys-loop receptors on cannabinoids: All high?Frontiers in physiology · 2022
    Pooled it
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Update on Cannabidiol in Drug-Resistant Epilepsy.Indian journal of pediatrics · 2025
    Review
  10. Article
  11. Research and Clinical Practice Involving the Use ofPharmaceuticals (Basel, Switzerland) · 2024
    Review
  12. Review
  13. Review
  14. Article
  15. Potential of CBD Acting on Cannabinoid Receptors CBInternational journal of molecular sciences · 2024
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Christopher Martínez-AguirreDepartment of Pharmacobiology, Center for Research and Advanced Studies, Mexico City, Mexico.
Francia Carmona-CruzDepartment of Pharmacobiology, Center for Research and Advanced Studies, Mexico City, Mexico.
Ana Luisa VelascoEpilepsy Clinic, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico.
Francisco VelascoEpilepsy Clinic, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico.
Gustavo Aguado-CarrilloEpilepsy Clinic, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico.
Manola Cuéllar-HerreraEpilepsy Clinic, Hospital General de México Dr. Eduardo Liceaga, Mexico City, Mexico.
Luisa RochaDepartment of Pharmacobiology, Center for Research and Advanced Studies, Mexico City, Mexico.
Hospital General de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental evidence indicates that cannabidiol (CBD) induces anxiolytic and antiepileptic effects through the activation of 5-HT

Indexed as

5-HT1A receptorcannabidioldrug-resistant epilepsyhippocampusmesial temporal lobe epilepsyserotonintemporal neocortex

Identifiers

PMID33384591
PMCPMC7770178
OpenAlexW3112635409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.