Evidence map›Paper›PMID 33384549›Full record

ReviewWorld journal of gastroenterology2020

Invasive fungal infection before and after liver transplantation.

Alberto Ferrarese, Annamaria Cattelan, Umberto Cillo, Enrico Gringeri, Francesco Paolo Russo, Giacomo Germani, Martina Gambato, Patrizia Burra, Marco Senzolo

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
0.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 47 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Critical care management of acute liver failure.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  9. Article
  10. Fungal infections in liver cirrhosis.Translational gastroenterology and hepatology · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. [Consensus on diagnosis and treatment of invasive fungal infection in patients with severe liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Alberto FerrareseMultivisceral Transplant Unit, Padua University Hospital, Padua 35128, Italy. alberto.ferrarese17@gmail.com.
Annamaria CattelanTropical and Infectious Disease Unit, Padua University Hospital, Padua 35128, Italy.
Umberto CilloPadua University Hospital, Hepatobiliary Surgery and Liver Transplant Center, Padua 35128, Italy.
Enrico GringeriPadua University Hospital, Hepatobiliary Surgery and Liver Transplant Center, Padua 35128, Italy.
Francesco Paolo RussoMultivisceral Transplant Unit, Padua University Hospital, Padua 35128, Italy.
Giacomo GermaniMultivisceral Transplant Unit, Padua University Hospital, Padua 35128, Italy.
Martina GambatoMultivisceral Transplant Unit, Padua University Hospital, Padua 35128, Italy.
Patrizia BurraMultivisceral Transplant Unit, Padua University Hospital, Padua 35128, Italy.
Marco SenzoloMultivisceral Transplant Unit, Padua University Hospital, Padua 35128, Italy.
Jackson and Tull (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive infections are a major complication before liver transplantation (LT) and in the early phase after surgery. There has been an increasing prevalence of invasive fungal disease (IFD), especially among the sickest patients with decompensated cirrhosis and acute-on-chronic liver failure, who suffer from a profound state of immune dysfunction and receive intensive care management. In such patients, who are listed for LT, development of an IFD often worsens hepatic and extra-hepatic organ dysfunction, requiring a careful evaluation before surgery. In the post-transplant setting, the burden of IFD has been reduced after the clinical advent of antifungal prophylaxis, even if several major issues still remain, such as duration, target population and drug type(s). Nevertheless, the development of IFD in the early phase after surgery significantly impairs graft and patient survival. This review outlines presentation, prophylactic and therapeutic strategies, and outcomes of IFD in LT candidates and recipients, providing specific considerations for clinical practice.

Indexed as

Invasive Fungal InfectionsLiver TransplantationMycosesAntifungal AgentsHumansAntifungal AgentsAcute liver failureAcute-on-chronic liver failureCandidemiaCirrhosisInvasive fungal infectionSepsis

Identifiers

PMID33384549
PMCPMC7754548
OpenAlexW3116583743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.